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Rabbit Anti-SRR Polyclonal Antibody#abs139402

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Description

Catalog-specification	Delivery time	USD price
abs139402-100ug	1-2 Weeks	301.0
abs139402-50ug	1-2 Weeks	201.0

Overview
catalog	abs139402
Other names	Serine racemase, also known as srr or SRR_HUMAN, is an enzyme involved in the conversion of D-serine to L-serine. It is also referred to as D serine ammonia lyase or D serine dehydratase. Another name for this enzyme is ILV1 or ISO1. Similarly, L-serine ammonia lyase and L-serine dehydratase are alternative names for the same enzyme. These enzymes play a crucial role in the metabolism of serine in the human body. By rearranging the given content, we can summarize it as follows: Serine racemase, also called srr or SRR_HUMAN, is an enzyme known as D-serine ammonia lyase or D-serine dehydratase. It is also referred to as ILV1 or ISO1. Similarly, L-serine ammonia lyase and L-serine dehydratase are alternative names for this enzyme. Through its metabolic role, serine racemase converts D-serine to L-serine.
Source	Rabbit
Specificity	The detection of endogenous levels of total SRR can be achieved using the SRR Antibody. To convey the same information in a highly similar manner, the content can be rephrased as follows: The presence of total SRR, at its natural levels within a biological system, can be effectively determined using the SRR Antibody.
Species Reactivity	Human
Antigen	SRR
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human SRR.
MW	37 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the purification of the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the quality of the product, it is recommended to store it at -20 °C for one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles.
Storage buffer	This solution contains Rabbit IgG suspended in a phosphate buffered saline with a pH of 7.4, 150mM of NaCl, and 0.02% of sodium azide. It also contains 50% glycerol for stability. It is advised to store this at -20°C, and it should remain stable for up to 12 months from the date of receipt.
Target
Background	Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Tissue specificity	Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
Posttranslational modification	S-nitrosylated, leading to decrease the enzyme activity.
Celluar localization	Plasma Membrane;
UniPort	Q9GZT4