Rabbit Anti-SIRPB1 Polyclonal Antibody#abs134809
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Description
| Catalog-specification | Delivery time | USD price |
abs134809-100ug | 1-2 Weeks | 301.0 |
abs134809-50ug | 1-2 Weeks | 201.0 |
Please note that the provided price is for your reference only. For detailed pricing information, please reach out to our seller, Vecent. In order to generate a significantly different content based on the original text, we can rephrase it as follows: "Please be advised that the price mentioned above serves as a general reference. To obtain specific pricing details, we kindly request you to contact our seller, Vecent."
| Overview | |
catalog | abs134809 |
| Other names | The CD172 antigen, also known as CD172b, is a protein that belongs to the CD172 antigen family. It is also referred to as signal regulatory protein beta 1 or SIRP beta 1 isoform 3. Another name for it is DKFZp686A05192. This protein plays a vital role in regulating the immune system and is a key player in controlling self-tolerance. CD172 antigen-like family member B is essential for recognizing self from non-self cells, which means it can identify foreign bodies and stimulate an immune response to protect the body from harmful invaders. CD172b is highly similar to other proteins in the CD172 family and shares many common features with them. Understanding the role of CD172b can potentially lead to the development of new therapies for various medical conditions. |
| Source | Rabbit |
| Specificity | The total levels of endogenous SIRPB1 can be accurately detected using the SIRPB1 Antibody. The antibody specifically targets and identifies the complete SIRPB1 protein present within the cells. Its application allows for the precise measurement of SIRPB1 levels in biological samples. |
| Species Reactivity | Human;Rat |
| Antigen | SIRPB1 |
| Application | /（IF/ICC），1:1001:500。（ELISA），1:200001:40000。，1:5001:1000，WB（Western Blot）。。 |
| Immunogen | A synthesized peptide. |
| MW | 48 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | SulfoLink™ Coupling Resin was used for peptide affinity chromatography to purify the antiserum. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To preserve the product's integrity, it's recommended to store it at a temperature of -20°C for a period of one year. Be sure to avoid subjecting it to repeated cycles of freezing and thawing. Following these guidelines will help maintain the quality of the product and ensure its efficacy when used. |
| Storage buffer | This product is Rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this product at a temperature of -20°C and it is known to be stable for up to 12 months from the date of receipt. |
Target | |
Background | This cell surface receptor, bearing immunoglobulin-like characteristics, plays a crucial role in controlling various signaling pathways associated with receptor tyrosine kinases. Its main function entails the inhibition of these signaling processes, thus regulating cellular responses. Furthermore, this receptor also actively participates in the recruitment of the tyrosine kinase known as SYK, forming an essential interaction that influences downstream cellular events. To summarize, this receptor exerts negative regulation on receptor tyrosine kinase-coupled signaling and facilitates the recruitment of SYK tyrosine kinase. |
| Tissue specificity | Detected in monocytes and dendritic cells. |
| Posttranslational modification | N-glycosylated. |
| Celluar localization | Extracellular region or secreted;Plasma Membrane; |
| UniPort | O00241 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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