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Rabbit Anti-RASGEF1B Polyclonal Antibody#abs139328

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Description

Catalog-specification	Delivery time	USD price
abs139328-100ug	1-2 Weeks	301.0
abs139328-50ug	1-2 Weeks	201.0

Overview
catalog	abs139328
Other names	FLJ31695, also known as GPI gamma-4 or GPIG4, is a protein encoded by the MGC46251 gene in humans. This protein belongs to the Ras-GEF domain-containing family and is also referred to as RasGEF domain family member 1B or RASGEF1B. The official symbol for this gene is RGF1B_HUMAN.
Source	Rabbit
Specificity	The RASGEF1B Antibody is designed to identify the levels of total RASGEF1B in the body's natural state. This means that it has the ability to detect the molecule regardless of its concentration in the samples being tested. Whether the amount is high or low, this antibody has the capability to accurately assess the total RASGEF1B in the samples.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Xenopus;Sheep;Dog;Bovine;Horse;
Antigen	RASGEF1B
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human RASGEF1B.
MW	55 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in order to purify the antiserum. This process ensured the production of a high-quality and targeted antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	The recommended storage temperature for one year is -20 °C. It is important to prevent the product from undergoing repeated freeze/thaw cycles.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at -20°C in phosphate buffered saline with a pH value of 7.4. The buffer should contain 150mM NaCl and 0.02% sodium azide along with 50% glycerol. This product is stable for a period of 12 months from the date of receipt. It is important to adhere to these storage guidelines to ensure the integrity and functionality of the Rabbit IgG.
Target
Background	Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
Tissue specificity	Up-regulated in macrophages stimulated with IFNG, GPI-mucins or bacterial lipopolysaccharides (LPS).
Celluar localization	Endosome;
UniPort	Q0VAM2