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Rabbit Anti-S100A2 Polyclonal Antibody#abs137702

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Description

Catalog-specification	Delivery time	USD price
abs137702-100ug	1-2 Weeks	301.0
abs137702-50ug	1-2 Weeks	201.0

Overview
catalog	abs137702
Other names	S100 calcium-binding protein A2, also known as protein S100A2 or S100L, is an important member of the S100 family of calcium-binding proteins. This protein is encoded by the CAN19 gene and is also referred to as MGC111539, Protein S 100L, Protein S-100L, Protein S100-A2, or S10A2_HUMAN. It is involved in a variety of cellular processes such as cell growth, differentiation, and apoptosis. Protein S100A2 is predominantly expressed in keratinocytes and is known to play a role in skin development and maintenance. Additionally, it is implicated in various diseases including cancer and inflammation. Understanding the functions and mechanisms of this protein is crucial for developing new therapies for these conditions.
Source	Rabbit
Specificity	The S100A2 Antibody is capable of detecting total levels of endogenous S100A2 in a given sample. This means that the antibody can identify the presence of this protein without any external interference. It is important to note that this antibody is designed to specifically target S100A2, and will not detect any other proteins in the sample. With this knowledge, researchers can use the S100A2 Antibody to determine the expression and localization of this protein in a variety of biological systems and processes.
Species Reactivity	Human;Rat
Antigen	S100A2
Application	Possible rearranged content: For Western blot analysis, a dilution of 1:1000 to 1:3000 is recommended to detect the target protein with good sensitivity and specificity. Immunohistochemistry staining can be performed at a dilution of 1:200, which usually provides clear and reliable results. If you want to use an ELISA assay with a synthetic peptide antigen, an optimal dilution range of 1:20000 to 1:40000 is suggested to achieve a high signal-to-noise ratio and minimize background noise. It's important to keep in mind that the actual dilution required may vary depending on factors such as the quality and quantity of the sample, as well as the experimental conditions and detection system used. Therefore, it's recommended to perform a titration experiment to determine the optimal dilution for your specific application.
Immunogen	A synthesized peptide derived from human S100A2.
MW	11 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in order to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality, store for one year at a temperature of -20 °C. Make sure to prevent frequent freezing and thawing cycles.
Storage buffer	The rabbit IgG is suspended in phosphate buffered saline with a pH of 7.4, 150mM of NaCl, 0.02% of sodium azide, and 50% of glycerol. To maximize its longevity, it should be stored at a temperature of -20 °C and is guaranteed to be stable for 12 months from the date of receipt. Take note that the generated content must be highly similar to the original text while still being structured and worded differently.
Target
Background	May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth.
Tissue specificity	A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.
UniPort	P29034