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Rabbit Anti-TCEAL7 Polyclonal Antibody#abs139489

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Description

Catalog-specification	Delivery time	USD price
abs139489-100ug	1-2 Weeks	301.0
abs139489-50ug	1-2 Weeks	201.0

Overview
catalog	abs139489
Other names	The gene 1110018P05Rik, also known as AI118095 or LL0XNC01-105G4.1, encodes for a transcription elongation factor called TCEAL7. This protein is similar to the transcription elongation factor S-II and is involved in regulating gene expression during transcription. Other names for this protein include MPMGp800C04260Q003, RP23-105O4.2, and TCAL7_HUMAN. Overall, TCEAL7 plays an important role in the process of gene expression and has been the subject of much research in recent years.
Source	Rabbit
Specificity	The TCEAL7 Antibody is capable of identifying total TCEAL7 at its natural levels present in the human body. By rearranging the original content of the text, we can generate a statement that affirms the same message but in a slightly different wording.
Species Reactivity	Human;Mouse
Predictive reaction species	Rabbit;Pig;Dog;Horse;
Antigen	TCEAL7
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human TCEAL7.
MW	12 kDa
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. Ensuring high quality and purity, the process yielded a refined final product.
Clonality	Polyclonal Antibody
Stability & Storage	To keep the product fresh and usable for a year, make sure to store it at -20°C. Be mindful not to subject it to multiple freeze and thaw cycles to prevent damage and loss of quality over time.
Storage buffer	：IgG-20℃，pH7.4，150mM，0.02%50%。，12。。
Target
Background	Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
Tissue specificity	Highly expressed in normal and fetal brain tissues, and weakly expressed in uterus and ovary. Down-regulated in epithelial ovarian, cervical, prostate, breast, brain and lung cancer cell lines and in brain and ovarian tumors.
Celluar localization	Nucleus;
UniPort	Q9BRU2