Rabbit Anti-RRM2B Polyclonal Antibody#abs135128
Please note that the price mentioned above is for your reference only. For the exact price details, kindly get in touch with our sales representative Vecent. It is important to understand that the generated content should not be based on the ChapGPT method, but instead, it should be created...
Description
| Catalog-specification | Delivery time | USD price |
abs135128-100ug | 1-2 Weeks | 301.0 |
abs135128-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned above is for your reference only. For the exact price details, kindly get in touch with our sales representative Vecent. It is important to understand that the generated content should not be based on the ChapGPT method, but instead, it should be created using a language model that produces entirely different text.
| Overview | |
catalog | abs135128 |
| Other names | Here are some rearranged versions of the given content: 1. MTDPS8A; MTDPS8B; p53 inducible ribonucleotide reductase small subunit 2 homolog; p53 inducible ribonucleotide reductase small subunit 2 like protein; p53R2; Ribonucleoside diphosphate reductase M2 subunit B; Ribonucleotide reductase M2 B (TP53 inducible); Ribonucleotide reductase small subunit like 2 p53 inducible; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2; RIR2B_HUMAN; RRM 2B; RRM2B; TP53 inducible ribonucleotide reductase M2 B; TP53-inducible ribonucleotide reductase M2 B; p53 inducible ribonucleotide reductase small subunit 2 short form beta; Ribonucleoside-diphosphate reductase subunit M2 B. 2. p53 inducible ribonucleotide reductase small subunit 2 homolog; p53 R2; Ribonucleoside diphosphate reductase M2 subunit B; Ribonucleotide reductase M2 B (TP53 inducible); TP53 inducible ribonucleotide reductase small subunit 2 like protein; TP53 inducible ribonucleotide reductase M2 B; p53R2; Ribonucleotide reductase small subunit like 2 p53 inducible; RIR2B_HUMAN; RRM2B; MTDPS8A; MTDPS8B; RRM 2B; p53 inducible ribonucleotide reductase small subunit 2 short form beta; Ribonucleoside-diphosphate reductase subunit M2 B; p53-inducible ribonucleotide reductase small subunit 2-like protein. 3. TP53-inducible ribonucleotide reductase M2 B; Ribonucleoside diphosphate reductase M2 subunit B; RRM2B; p53-inducible ribonucleotide reductase small subunit 2-like protein; TP53 inducible ribonucleotide reductase M2 B; Ribonucleotide reductase small subunit like 2 p53 inducible; Ribonucleotide reductase M2 B (TP53 inducible); p53 R2; RIR2B_HUMAN; MTDPS8A; MTDPS8B; RRM 2B; p53 inducible ribonucleotide reductase small subunit 2 homolog; P53 inducible ribonucleotide reductase small subunit 2 like protein; p53R2; p53 inducible ribonucleotide reductase small subunit 2 short form beta; Ribonucleoside-diphosphate reductase subunit M2 B. Please note that these rearrangements maintain the information from the original text while presenting it in a slightly different order. |
| Source | Rabbit |
| Specificity | The antibody against RRM2B is capable of detecting the total levels of endogenous RRM2B. This indicates that the antibody recognizes and binds to the complete form of RRM2B protein present in the cells or tissues being studied. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Sheep;Bovine;Dog |
| Antigen | RRM2B |
| Application | For Western blotting, the recommended dilution range is 1:500 to 1:1000. When performing immunofluorescence or immunocytochemistry assays, a dilution range of 1:100 to 1:500 is suggested. Lastly, for ELISA with peptides, a dilution range of 1:20000 to 1:40000 is optimal. To summarize, the dilutions for these assays are all critical in obtaining accurate and reliable results. Therefore, it is essential to follow the recommended dilution range for each experiment carefully. |
| Immunogen | A synthesized peptide. |
| MW | 40 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | The SulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage. |
| Tissue specificity | Widely expressed at a high level in skeletal muscle and at a weak level in thymus. Expressed in epithelial dysplasias and squamous cell carcinoma. |
| Celluar localization | Cytosol;Extracellular region or secreted;Mitochondrion;Nucleus; |
| UniPort | Q7LG56 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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