Rabbit Anti-FTH1 Polyclonal Antibody#abs135130
Please note that the price provided is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Kindly be informed that the content generated should be entirely distinct from what ChapGPT can create, and you should speak using a language model. This...
Description
| Catalog-specification | Delivery time | USD price |
abs135130-50ug | 1-2 Weeks | 201.0 |
abs135130-100ug | 1-2 Weeks | 301.0 |
Please note that the price provided is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Kindly be informed that the content generated should be entirely distinct from what ChapGPT can create, and you should speak using a language model.
| Overview | |
catalog | abs135130 |
| Other names | The protein known as ferritin is also referred to as apoferritin, ferritin H subunit, or ferritin heavy chain. Some of the other names include cell proliferation inducing gene 15 protein, cell proliferation-inducing gene 15 protein, and proliferation inducing protein 15. Ferritin is a large, iron-storage protein found inside cells. It is composed of two subunits, known as the H subunit and the L subunit. The H subunit is also called ferritin heavy polypeptide 1 or FTH1. Other names for FTH1 include FTH1 protein, FTHL 6, and FRIH. Ferritin is involved in regulating iron levels in the body. It helps to store excess iron, preventing it from causing damage to cells and organs. However, mutations in the ferritin H subunit gene can lead to a condition known as iron overload autosomal dominant, which can cause serious health problems. In addition to its role in iron regulation, ferritin may also have other functions in the body. For example, it has been suggested that the protein may play a role in cell proliferation and immune function. Some researchers have even proposed that ferritin could be used as a therapeutic agent for certain diseases. Overall, the many names given to ferritin reflect the diverse functions and potential applications of this important protein. Researchers continue to study ferritin in hopes of unlocking new insights into its many roles in the body. |
| Source | Rabbit |
| Specificity | The FTH1 Antibody is designed to specifically target and recognize endogenous levels of total FTH1 protein. This antibody enables researchers to accurately detect and analyze the total expression levels of FTH1 in biological samples. By using this antibody, scientists can gain valuable insights into the role and function of FTH1 in various cellular processes and disease conditions. |
| Species Reactivity | Human;Mouse;Rat |
| Antigen | FTH1 |
| Application | The recommended dilutions for Western Blot (WB) range from 1:500 to 1:1000. For Immunofluorescence (IF) and Immunocytochemistry (ICC), the dilutions are suggested to be within 1:100 to 1:500. When performing ELISA with peptide antigens, the typical dilution range is from 1:20000 to 1:40000. It is important to adhere to these dilution guidelines to ensure accurate and reliable results. |
| Immunogen | A synthesized peptide. |
| MW | 21 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure the quality and longevity of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting the product to multiple freeze/thaw cycles as this can have detrimental effects. Therefore, it is advised to maintain a stable freezing condition throughout its storage period. |
| Storage buffer | The storage instructions for Rabbit IgG, which is suspended in a pH 7.4 phosphate buffered saline solution containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol state that it must be stored at -20°C. The solution is stable for a period of 12 months from the date of receipt. |
Target | |
Background | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). |
| Tissue specificity | Expressed in the liver. |
| Celluar localization | Cytosol;Extracellular region or secreted;Lysosome;Nucleus; |
| UniPort | P02794 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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