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Rabbit Anti-DAK Polyclonal Antibody #abs130493

Please note that the price mentioned above is only provided for your reference. For detailed pricing information, we kindly request you to contact our seller, Vecent. Thank you. Data Examples Western blot analysis on K562 cell lysate using DAK Antibody This product is for research use only, not...

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Description

Catalog-specification	Delivery time	USD price
abs130493-50ug	1-2 Weeks	201
abs130493-100ug	1-2 Weeks	301

Please note that the price mentioned above is only provided for your reference. For detailed pricing information, we kindly request you to contact our seller, Vecent. Thank you.

Overview
Description	The enzyme DAK plays a crucial role in the process of phosphorylating dihydroxyacetone. This chemical reaction is catalyzed by DAK, which facilitates the transformation of dihydroxyacetone into another compound by adding a phosphate group. The process of catalysis by DAK involves a series of biochemical reactions that occur in a specific order and require precise conditions to be successful. The phosphorylation of dihydroxyacetone is essential for various biological processes and is of great importance in the fields of biochemistry and biotechnology.
Other names	This protein is known as an ATP dependent dihydroxyacetone kinase, also referred to as DAK or dihydroxyacetone kinase 2 homolog in yeast. It is also bifunctional, playing a role as both a dihydroxyacetone kinase and FAD AMP lyase (cyclizing). This multifaceted enzyme also acts as an FMN cyclase and a glycerone kinase. Its function involves the phosphorylation of dihydroxyacetone, an intermediate in the glycolytic pathway. The activity of this enzyme is dependent on ATP, and it is responsible for the conversion of dihydroxyacetone to dihydroxyacetone phosphate. Additionally, it is involved in the cyclic formation of FMN and the conversion of FAD to AMP. This versatile protein plays a crucial role in various metabolic processes, making it a vital component in cellular function and survival.
Source	Rabbit
Specificity	DAK Antibody detects endogenous levels of DAK
Species Reactivity	Human;Mouse;Rat
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human DAK
Properties
Concentration	1mg/ml
Purification	Immunogen affinity purified
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the preservation of the item, it is important to store it at a temperature of -20 °C for a period of one year. It is also crucial to avoid subjecting it to repeated cycles of freezing and thawing.
Storage buffer	This product is Rabbit IgG in phosphate buffered saline at pH 7.4 with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store the product at -20 °C for optimal stability. The product remains stable for a period of 12 months from the date of receipt.
Target
Background	This enzyme is capable of catalyzing the phosphorylation of both dihydroxyacetone and glyceraldehyde. Additionally, it is also responsible for the splitting of ribonucleoside diphosphate-X compounds, with FAD being the most favorable substrate among them. Its functionality extends to repressing the IFIH1-mediated cellular antiviral response, as evidenced in a research study cited in PubMed (PubMed:17600090). By reorganizing the given information, a highly similar content can be generated.
Tissue specificity	Detected in erythrocytes (at protein level).
Celluar localization	Cytosol;Extracellular region or secreted;Nucleus;
UniPort	Q3LXA3