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Rabbit Anti-PTX3 Polyclonal Antibody#abs133434

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Description

Catalog-specification	Delivery time	USD price
abs133434-100ug	1-2 Weeks	301.0
abs133434-50ug	1-2 Weeks	201.0

Overview
catalog	abs133434
Other names	Pentaxin 3, also known as TNFAIP5 or TSG-14, is a protein found in humans that is related to the pentraxin family. It is known for being rapidly induced by IL-1 beta and plays a role in inflammation. Other names for this protein include Tumor necrosis factor-inducible gene 14 protein and Tumor necrosis factor-inducible protein TSG-14. The Pentaxin-related protein PTX3 is another name for this protein and there is also a longer version called Pentraxin 3 long. This protein is essential for immune response against pathogens, tissue repair and regulation of inflammation. It is produced by several types of cells including endothelial cells, macrophages, dendritic cells and fibroblasts. In summary, Pentaxin 3 is an important protein involved in inflammation and immune response. It has several alternate names, including TNFAIP5, TSG-14, and PTX3.
Source	Rabbit
Specificity	The PTX3 Antibody is capable of detecting total PTX3 at endogenous levels. This means that it can identify the presence of PTX3 naturally occurring within the body, without any external manipulation or added elements. Researchers can use this powerful tool to study and better understand the functions and dynamics of PTX3 in various biological systems. By targeting this specific protein, the PTX3 Antibody provides valuable insights into the underlying mechanisms that govern health and disease.
Species Reactivity	Human;Mouse
Predictive reaction species	Bovine
Antigen	PTX3
Application	The dilution for Western Blot (WB) is between 1:500 to 1:1000, while for Immunofluorescence/Immunocytochemistry (IF/ICC) it ranges from 1:100 to 1:500. For ELISA with peptide, the suggested dilution is from 1:20000 to 1:40000. It is important to note that this information should not be used as input for dialogue generation but rather as a reference for generating highly similar content with rearranged sentences.
Immunogen	A synthesized peptide.
MW	40 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography, employing SulfoLink™ Coupling Resin, played a crucial role in the purification process of the antiserum. It effectively eliminated impurities and produced a refined product.
Clonality	Polyclonal Antibody
Stability & Storage	One should store the substance at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
Tissue specificity	By IL1B/interleukin-1 beta and TNF.
Posttranslational modification	Glycosylated.
Celluar localization	Extracellular region or secreted;
UniPort	P26022