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Rabbit Anti-MAP4K5 Polyclonal Antibody#abs132732

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Description

Catalog-specification	Delivery time	USD price
abs132732-100ug	1-2 Weeks	301.0
abs132732-50ug	1-2 Weeks	201.0

Overview
catalog	abs132732
Other names	MEKKK 5, also known as KHS, Kinase homologous to SPS1/STE20, MAPK/ERK kinase kinase kinase 5, or MEK kinase kinase 5, is an important member of the MAP kinase signaling pathway. This protein plays a crucial role in transducing extracellular signals to the nucleus, ultimately resulting in the activation of target genes. MEKKK 5 is involved in a variety of cellular processes, including cell proliferation, differentiation, apoptosis, and stress responses. This enzyme is also implicated in the development of several diseases, such as cancer, autoimmune disorders, and neurological disorders. Understanding the function and regulation of MEKKK 5 is critical for developing effective therapies for these diseases.
Source	Rabbit
Specificity	The detection of total MAP4K5 at its endogenous levels is achieved by using the MAP4K5 antibody. Let me generate a highly similar content by rearranging the original information: The total MAP4K5 present naturally within the system can be accurately identified through the application of the MAP4K5 antibody.
Species Reactivity	Human;Mouse
Antigen	MAP4K5
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	95 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain quality, it is recommended to store the product at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles, as it can affect its stability and effectiveness. Therefore, proper storage conditions should be maintained to ensure the product is kept in optimal condition.
Storage buffer	The solution is composed of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol.
Target
Background	Appearing to have a role in responding to environmental stress, it is suggested that it functions before the JUN N-terminal pathway. Arranging the provided information differently, we can say that it is relevant in addressing environmental stress and is believed to operate upstream of the JUN N-terminal pathway.
Tissue specificity	Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.
UniPort	Q9Y4K4