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Rabbit Anti-RXRgamma Polyclonal Antibody#abs140545

Please note that the price mentioned above is for your reference only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis RXRgamma using HepG2 whole cell lysates This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs140545-100ug	1-2 Weeks	301.0
abs140545-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is for your reference only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs140545
Other names	NR2B3, also known as RXR gamma or Retinoid X receptor gamma, is a member of the Nuclear receptor subfamily 2 group B. It serves as a transcription factor that regulates gene expression and contributes to various physiological processes. The protein encoded by NR2B3 is involved in the regulation of cell proliferation, differentiation, and apoptosis. It is also crucial for the development of several organs, including the skin, liver, and central nervous system. Furthermore, NR2B3 is involved in the signaling pathway of retinoids, a class of compounds derived from vitamin A that play crucial roles in vision, growth, and development. The retinoid signaling mediated by NR2B3 is crucial for the proper functioning of various tissues, including the skin, eyes, and immune system. In summary, NR2B3 is a vital transcription factor that plays a crucial role in the regulation of gene expression and physiological processes. Its involvement in the retinoid signaling pathway makes it critical for the proper functioning of various organs, including the skin, liver, and central nervous system.
Source	Rabbit
Specificity	The endogenous levels of total RXRgamma can be detected using the RXRgamma Antibody. By employing this antibody, one can accurately measure the presence of RXRgamma in biological samples.
Species Reactivity	Human;Rat
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Sheep;Bovine;Horse
Antigen	RXRgamma
Application	The suggested dilutions for Western Blot (WB) are 1:1000, for Immunofluorescence/Immunocytochemistry (IF/ICC) they range from 1:100 to 1:500, and for Enzyme-linked immunosorbent assay (ELISA) utilizing peptides, the dilutions are between 1:20000 and 1:40000.
Immunogen	A synthesized peptide derived from human RXRgamma.
MW	50kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to perform peptide affinity chromatography and purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. One should take care to avoid subjecting the product to frequent changes in temperature, as these may cause damage and affect the efficacy of the product. It is therefore advised to avoid repeated freeze/thaw cycles, in order to ensure that the product remains viable and effective for its intended purpose.
Storage buffer	The product is Rabbit IgG, which is stored in phosphate-buffered saline (pH 7.4) containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and has a shelf life of 12 months from the date of receipt.
Target
Background	Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).
Celluar localization	Nucleus;
UniPort	P48443