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Rabbit Anti-PROX1 Polyclonal Antibody#abs137866

Dear valued customer, please note that the price provided is for your reference only. For detailed pricing information, kindly contact our esteemed seller, Vecent. Thank you for your understanding. Western blot analysis PROX1 using LOVO whole cell lysates This product is for research use only,...

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Description

Catalog-specification	Delivery time	USD price
abs137866-100ug	1-2 Weeks	301.0
abs137866-50ug	1-2 Weeks	201.0

Dear valued customer, please note that the price provided is for your reference only. For detailed pricing information, kindly contact our esteemed seller, Vecent. Thank you for your understanding.

Overview
catalog	abs137866
Other names	Prox1, also known as Homeobox prospero-like protein, is a vital protein involved in various cellular processes. It plays a significant role in development and differentiation. The Prospero homeobox protein 1, encoded by the PROX1 gene, regulates gene expression and controls the fate of specific cell types. PROX1 is a crucial factor in the formation of organs and tissues during embryonic development. The PROX1 protein is highly conserved in evolution and is essential for normal development and function of various tissues, including the central nervous system and lymphatic system. In summary, PROX1, a prospero-related homeobox gene, is an important player in embryonic development and cellular differentiation processes. Its presence and regulation are essential for the proper functioning of various tissues and organs.
Source	Rabbit
Specificity	The PROX1 Antibody is capable of detecting the overall amount of PROX1 protein present in the body. It specifically targets the endogenous levels of PROX1, allowing researchers to accurately measure its total expression. By using the PROX1 Antibody, scientists can gain valuable insights into the role and function of PROX1 in various biological processes.
Species Reactivity	Human
Predictive reaction species	Rabbit;Pig;Dog;Horse;
Antigen	PROX1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human PROX1.
MW	83 kDa
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, the purification process of the antiserum involved peptide affinity chromatography. To ensure optimal quality, the original content was rearranged while accurately reflecting the information provided.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated cycles of freezing and thawing, as this can affect its composition and integrity. Taking the necessary precautions will help ensure that the product remains stable and effective for its intended use.
Storage buffer	This is a description of Rabbit IgG stored in a specific solution. The Rabbit IgG is dissolved in phosphate buffered saline and has a pH of 7.4. The solution also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this solution at a temperature of -20 °C. The stability of the Rabbit IgG is guaranteed for a period of 12 months from the date of receipt.
Target
Background	Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
Tissue specificity	Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.
Celluar localization	Nucleus;
UniPort	Q92786