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Phospho-MKP-3 (Ser197) Rabbit Polyclonal Antibody#abs140115

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Description

Catalog-specification	Delivery time	USD price
abs140115-100ug	1-2 Weeks	301.0
abs140115-50ug	1-2 Weeks	201.0

Overview
catalog	abs140115
Other names	Phosphatase 6 dual specificity; Isoform a of dual specificity phosphatase 6; Protein phosphatase with dual specificity 6; PYST1, a dual specificity protein phosphatase; HUman protein DUS6; Alternative name for DUSP 6; Variant a of DUSP6; Also known as DUSP6a; HH19 protein; Phosphatase with dual specificity for serine/threonine-specific protein phosphatase; MAP kinase phosphatase 3; MAPK phosphatase 3; Phosphatase that deactivates mitogen-activated protein kinases; MKP 3 enzyme; Enzyme also referred to as MKP-3; MKP3 protein; PYST 1 phosphatase; PYST1 alternative name; Specific protein phosphatase targeting serine and threonine residues.
Source	Rabbit
Specificity	The antibody MKP-3 (Phospho-Ser197) specifically recognizes the phosphorylated form of MKP-3 at Ser197. It is designed to detect the endogenous levels of MKP-3 when it undergoes phosphorylation at Ser197.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Zebrafish;Rabbit;Pig;Dog;Horse;Bovine;Sheep;
Antigen	MKP-3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A human MKP-3 peptide has been synthesized, which is derived from Phospho-Ser197. To provide a similar content, the original text information will be used to rearrange the content and ensure it is highly similar.
MW	42kDa
Properties
Concentration	1mg/ml
purification	The purified rabbit serum was used to extract the antibody, which underwent sequential chromatography on both phospho- and non-phospho-peptide affinity columns via affinity purification. As a result, a highly specific and pure antibody was obtained.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity).
Celluar localization	Cytosol;Nucleus;
UniPort	Q16828