Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-POMC Polyclonal Antibody#abs133034

Please note that the price mentioned above is for your reference only. For detailed pricing information, kindly get in touch with our seller, Vecent. Please understand that the content generated must be significantly different from the original text and should not follow the conversation style...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs133034-50ug	1-2 Weeks	201.0
abs133034-100ug	1-2 Weeks	301.0

Overview
catalog	abs133034
Other names	Proopiomelanocortin, also known as POMC, is a protein precursor that is cleaved to produce several different peptide hormones. Among these hormones are beta-endorphin and corticotropin lipotropin. Beta-endorphin is an endogenous opioid peptide that is involved in pain regulation and reward processing. Corticotropin lipotropin, also known as CLIP, is involved in the regulation of inflammation and metabolism. Both of these peptides are derived from POMC and are important in the body's stress response and regulation of pain and inflammation.
Source	Rabbit
Specificity	The total POMC levels can be detected using the POMC antibody that specifically targets endogenous POMC.
Species Reactivity	Human;Mouse;Rat
Antigen	POMC
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	29 kDa
Properties
Concentration	1mg/ml
purification	Using the SulfoLink™ Coupling Resin, the antiserum was purified through peptide affinity chromatography. This process effectively isolated the desired components of the antiserum and removed any impurities, resulting in a highly purified product ready for use in research or medical applications.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20°C for a year. It is advisable to avoid subjecting the product to numerous freeze/thaw cycles as it may affect its efficacy and performance. Be sure to follow these storage instructions to ensure that the product remains viable and effective for future use.
Storage buffer	pH7.4、150mM NaCl、0.02%50%，IgG。，。
Target
Background	The hormone, corticotropin, has the ability to prompt the adrenal glands to secrete cortisol, which is a hormone that plays a crucial role in stress response and metabolic functions within the body.
Tissue specificity	ACTH and MSH are produced by the pituitary gland.
Posttranslational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides.O-glycosylated; reducing sugar is probably N-acetylgalactosamine.
Celluar localization	Extracellular region or secreted;Peroxisome;
UniPort	P01189