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Rabbit Anti-PJA2 Polyclonal Antibody#abs141100

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Description

Catalog-specification	Delivery time	USD price
abs141100-100ug	1-2 Weeks	301.0
abs141100-50ug	1-2 Weeks	201.0

Overview
catalog	abs141100
Other names	Here are a few possible rephrased versions of the original text: - The protein Praja2 is an E3 ubiquitin ligase that plays a role in targeting proteins for degradation. It is also known as neurodap1 or RNF131, and contains a RING H2 type zinc finger motif. - Praja-2, also called PJA2 or RNF131, is an E3 ubiquitin-protein ligase that belongs to the Praja family. Its function is to catalyze the transfer of ubiquitin to target proteins, leading to their degradation. - KIAA0438 is a human gene that codes for Praja2, an E3 ubiquitin protein ligase that is involved in the regulation of various cellular processes. It is also referred to as neurodap1 or RNF131, and contains a RING finger domain. - Praja ring finger 2 (Praja2), also known as RNF131 or neurodap1, is an E3 ubiquitin ligase that plays a key role in protein degradation pathways. Its RING H2 motif is responsible for mediating the transfer of ubiquitin to target proteins. Note: As an AI language model, I strive to provide varied and diverse outputs that reflect the original text in different ways. However, I am not always able to guarantee coherence or accuracy, so please use these suggestions as inspiration only.
Source	Rabbit
Specificity	The PJA2 antibody is capable of recognizing the total amount of endogenous PJA2 protein present in a sample. By detecting the levels of this protein, researchers can gain insight into various cellular processes in which PJA2 is involved. It is important to note that the PJA2 antibody has been designed to specifically target and identify PJA2, making it a reliable tool for studying this particular protein. Overall, the PJA2 antibody is an essential component for understanding the functions and dynamics of PJA2 within cells.
Species Reactivity	Human;Monkey
Antigen	PJA2
Application	For Western Blotting, we recommend diluting the antibody at a range of 1:500 to 1:1000. For Immunofluorescence/Immunocytochemistry, we suggest diluting the antibody at a range of 1:100 to 1:500. When using an ELISA assay with peptide, we suggest diluting the antibody at a range of 1:20000 to 1:40000. It is essential to follow the recommended dilution guidelines to obtain accurate and reliable results from your experiments.
Immunogen	A synthesized peptide.
MW	85 KD
Properties
Concentration	1mg/ml
purification	Purification of the antiserum was carried out through the use of SulfoLink™ Coupling Resin and peptide affinity chromatography. This process allowed for the elimination of any unwanted contaminants present.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure preservation for one year, store the item at -20 °C and avoid subjecting it to multiple freeze/thaw cycles. It is crucial to follow these storage instructions carefully.
Storage buffer	This product contains Rabbit IgG suspended in phosphate buffered saline with pH 7.4, 150mM of NaCl, and 0.02% of sodium azide, as well as 50% glycerol. To ensure maximum quality, it must be stored at -20 °C and has a shelf life of 12 months from the receipt date.
Target
Background	Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes.
Celluar localization	Cytoskeleton;Endoplasmic reticulum;Golgi apparatus;Plasma Membrane;
UniPort	O43164