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C/EBP-α (Phospho-Ser193) Antibody#abs139866

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Description

Catalog-specification	Delivery time	USD price
abs139866-100ug	In Stock	301.0
abs139866-50ug	In Stock	201.0

Overview
catalog	abs139866
Other names	C/EBP alpha, also known as CCAAT/enhancer-binding protein alpha, is a key regulator of gene expression, playing a crucial role in cellular differentiation and metabolic homeostasis. This transcription factor is encoded by the CEBPA gene and is part of the C/EBP family of bZIP transcription factors. Additionally, C/EBP alpha has been linked to the regulation of apoptosis, and is involved in the activation of apoptotic cysteine proteases, such as caspase 8 which is also known as FLICE. This protein is synthesized as a precursor and is cleaved into its active form during activation of the apoptotic pathway. Other proteins that have been associated with C/EBP alpha include FADD homologous ICE/CED 3 like protease, also known as MACH or MCH5, and MORT1 associated CED 3 homolog, also known as ICE-like apoptotic protease 5 or ICE8. Collectively, these proteins play crucial roles in programmed cell death and are essential for the maintenance of normal cellular physiology.
Source	Rabbit
Specificity	The C/EBP-α (Phospho-Ser193) Antibody specifically targets the phosphorylated form of C/EBP-α at Ser193. This antibody is capable of detecting endogenous levels of phosphorylated C/EBP-α.
Species Reactivity	Human;Mouse;Rat
Antigen	C/EBP-α
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A new peptide has been synthesized from human C/EBP-α, specifically targeting Phospho-Ser193. The peptide has been designed to be highly similar to the original protein, ensuring optimal binding and effectiveness. This synthesized peptide holds great promise for use in research and therapeutics, as it allows for precise targeting of specific aspects of the human C/EBP-α protein. By decoding and analyzing its structure, scientists have been able to create a cutting-edge treatment option that shows great potential in the field of medicine.
MW	37KD
Properties
Concentration	1mg/ml
purification	The purified rabbit serum was utilized to produce the antibody through affinity purification involving sequential chromatography on both phospho- and non-phospho-peptide affinity columns. The resulting antibody is highly specific and effective in its intended function, as it has been designed to recognize and target specific peptides with phosphorylation sites. The process of affinity purification ensures that the antibody is of the highest quality, with minimal impurities and an optimal balance of avidity and specificity. Overall, this approach provides a reliable and efficient means of generating antibodies for use in various biological applications.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
UniPort	P53566/P49715