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Rabbit Anti-PEG3 Polyclonal Antibody#abs140506

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Description

Catalog-specification	Delivery time	USD price
abs140506-100ug	1-2 Weeks	301.0
abs140506-50ug	1-2 Weeks	201.0

Overview
catalog	abs140506
Source	Rabbit
Specificity	The PEG3 Antibody is capable of detecting total PEG3 at its natural levels within the body. This means that the antibody is specifically designed to target endogenous levels of PEG3, allowing for accurate and reliable detection. By utilizing this antibody, researchers can gain valuable insights into the role and function of PEG3 in various physiological processes.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Pig;Dog;Horse;Bovine
Antigen	PEG3
Application	To perform western blotting, dilute the antibody at a ratio of 1:1000. For immunohistochemistry, the antibody should be diluted at 1:200 concentration. For immunofluorescence and immunocytochemistry, use 1:100-1:500 diluted antibody. If you plan to use ELISA with a peptide antigen, the recommended dilution is between 1:20000-1:40000. These dilutions are based on the original text information, which should be followed to achieve optimal results.
Immunogen	A synthesized peptide derived from human PEG3.
MW	181kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was achieved through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	The recommended storage condition for one year is at -20 °C. It is important to avoid subjecting the product to repeated freeze/thaw cycles.
Storage buffer	The storage condition for Rabbit IgG is at -20 °C in phosphate buffered saline with a pH of 7.4. It should be maintained in a solution containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This product remains stable for a period of 12 months starting from the date of receipt. Please note that it is crucial not to follow the same conversation generation method as ChapGPT, but instead, provide a completely different style of speech using the language model to generate highly similar content based on the original text information.
Target
Background	SIAH1A cooperates with p53/TP53 to induce apoptosis. It serves as a mediator in a DNA damage-induced neuronal death pathway, working in conjunction with BAX. Additionally, this protein enhances the anti-apoptotic effects of TRAF2 and prevents TNF-induced apoptosis by activating NF-kappa-B. Its presence also exerts a tumor-suppressing effect in glioma cells. By reorganizing the given information, a highly similar content can be generated.
Tissue specificity	Brain, glial cells, astrocytes, embryo, placenta, testis, ovary and uterus. In the placenta it is found in the layer of villous cytotrophoblast cells while in the ovary it is found in the cells of the ovarian stroma including the thecal layers around the follicles. Expression is highly repressed in glioma cell lines.
Celluar localization	Nucleus;
UniPort	Q9GZU2