Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-PDCD5 Polyclonal Antibody#abs132941

Please note that the price mentioned is only for your reference and for details, please get in touch with our seller, Vecent. Kindly rearrange the information provided to come up with a highly similar content. Additionally, it's crucial to ensure that the generated content isn't based on the...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs132941-100ug	1-2 Weeks	301.0
abs132941-50ug	1-2 Weeks	201.0

Overview
catalog	abs132941
Description	May function in the process of apoptosis.
Other names	Programmed cell death protein 5, also known as TFAR19 or TF-1 cell apoptosis-related protein 19, is a novel apoptosis-related protein that plays a crucial role in regulating cell survival and death. This protein is encoded by the PDCD5 gene and is highly conserved among vertebrates. PDCD5 has been shown to interact with various proteins involved in apoptosis, including caspase-3 and Bcl-2 family proteins. It has been suggested that PDCD5 may act as a pro-apoptotic factor by binding to and activating caspase-3, leading to programmed cell death. In addition to its role in apoptosis, PDCD5 has also been implicated in other cellular processes such as cell proliferation, differentiation, and DNA damage response. Studies have suggested that PDCD5 may function as a tumor suppressor by inhibiting cell proliferation and promoting cell cycle arrest. Overall, PDCD5 is a multifunctional protein with diverse roles in cellular processes. Further research is needed to fully understand the complex mechanisms by which PDCD5 regulates cell survival and death, and its potential implications in human diseases such as cancer.
Source	Rabbit
Specificity	The PDCD5 antibody is capable of detecting the complete levels of endogenous PDCD5 protein present within a sample. This means that it can accurately identify all forms and variants of PDCD5 that are naturally occurring in a given biological material.
Species Reactivity	Human;Mouse
Antigen	PDCD5
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	18 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed in the peptide affinity chromatography process to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	The recommended storage condition for one year is at -20 °C. It is important to avoid subjecting the stored item to repeated freeze/thaw cycles.
Storage buffer	The composition of the solution is as follows: 50% glycerol, phosphate buffered saline (pH 7.4), 150mM NaCl, 0.02% sodium azide, and Rabbit IgG.
Target
Background	May function in the process of apoptosis.
Tissue specificity	Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.
Celluar localization	Cytosol;Extracellular region or secreted;Nucleus;
UniPort	O14737