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Rabbit Anti-NMUR1 Polyclonal Antibody#abs140487

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Description

Catalog-specification	Delivery time	USD price
abs140487-100ug	1-2 Weeks	301.0
abs140487-50ug	1-2 Weeks	201.0

Overview
catalog	abs140487
Other names	The protein FM-3, also known as G protein-coupled receptor 66 or GPR66, is a member of the growth hormone secretagogue receptor family. Another name for this protein is Neuromedin U Receptor 1 or NMU-R1. The protein is important in the function of the neuromedin U receptor 1, which is responsible for mediating the effects of the neuromedin U hormone. The protein plays a crucial role in various physiological processes such as appetite control, energy metabolism, and the sleep-wake cycle. NMUR1 has been found to be associated with several disorders including anxiety, depression, and obesity. Despite limited information about FM-3, its potential involvement in various diseases makes it an important target for drug development.
Source	Rabbit
Specificity	The detection of endogenous levels of total NMUR1 can be achieved with the NMUR1 Antibody.
Species Reactivity	Human;Mouse;Rat
Antigen	NMUR1
Application	The recommended dilution ratios for WB, IHC, and ELISA(peptide) are 1:1000, 1:200, and 1:20000-1:40000, respectively. It is important to adhere to the recommended dilution ratios to ensure accurate and reliable results. For WB, the dilution ratio of 1:1000 is recommended to achieve optimal results. Similarly, for IHC, a dilution ratio of 1:200 is recommended to generate clear and precise staining. For ELISA(peptide), a dilution range of 1:20000-1:40000 is recommended, which should provide a suitable concentration range for accurate measurement of antigen-antibody interactions. Overall, it is crucial to follow the suggested dilution ratios to ensure quality data and reliable results.
Immunogen	A synthesized peptide derived from human NMUR1.
MW	48kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography for purification.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain quality, it is recommended to store at a temperature of -20 °C for a duration of one year. It is important to prevent repeated freezing and thawing cycles.
Storage buffer	This product is Rabbit IgG in phosphate buffered saline, with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. For optimal storage, it should be kept at -20°C, and is stable for up to 12 months from the date of receipt.
Target
Background	Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Tissue specificity	Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.
Celluar localization	Plasma Membrane;
UniPort	Q9HB89