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Rabbit Anti-NCAM2 Polyclonal Antibody#abs134526

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Description

Catalog-specification	Delivery time	USD price
abs134526-100ug	1-2 Weeks	301.0
abs134526-50ug	1-2 Weeks	201.0

Overview
catalog	abs134526
Other names	The neural cell adhesion molecule 2, also known as N-CAM-2 or RB8 neural cell adhesion molecule, is a cell adhesion molecule that plays a crucial role in neural development and function. It is encoded by the MGC51008 gene and has several other aliases, including N CAM 2, N CAM21, NCAM 21, and R4B12. N-CAM-2 is a glycosylated protein that is expressed in a variety of neural tissues. It belongs to the immunoglobulin superfamily of proteins and is involved in cell-cell interactions, signaling, and adhesion. N-CAM-2 is particularly important in neural development and synapse formation, as it is responsible for guiding growing axons and dendrites to their appropriate targets. In addition to its neural functions, N-CAM-2 has been implicated in cancer metastasis and immune system regulation. It has also been found to be expressed in other tissues, such as the heart, kidneys, and lungs. Overall, N-CAM-2 is a versatile and important protein that plays a critical role in neural development, signaling, and adhesion, as well as other physiological processes. Its numerous aliases reflect its diverse functions and underscores the importance of this molecule in various tissues and contexts.
Source	Rabbit
Specificity	Total NCAM2 levels can be detected using the NCAM2 Antibody, which specifically recognizes endogenous NCAM2 protein.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	NCAM2
Application	The dilution ratio for Western Blot is 1:500~1:1000. For Immunofluorescence/Immunocytochemistry, the dilution ratio is 1:100-1:500. For ELISA with peptide detection, the dilution ratio is 1:20000-1:40000.
Immunogen	A synthesized peptide.
MW	100 KD
Properties
Concentration	1mg/ml
purification	To obtain a purified antiserum, the SulfoLink™ Coupling Resin was employed for peptide affinity chromatography. This process involves attaching certain peptides to the resin, which selectively binds to the target antibodies. The resulting purified antiserum is high-quality and suitable for various downstream applications.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it in a freezer at a temperature of -20 °C for up to one year. It is important to avoid exposing the product to repeated freezing and thawing cycles, as this can compromise its integrity and efficacy. Therefore, it is crucial to follow the storage instructions to ensure that the product remains stable and effective for its intended use.
Storage buffer	Store this Rabbit IgG solution in phosphate buffered saline at a pH of 7.4, along with 150mM NaCl, 0.02% sodium azide, and 50% glycerol, making sure to keep it at -20°C. This solution should remain stable for up to 12 months from the date of receipt.
Target
Background	May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
Tissue specificity	Expressed most strongly in adult and fetal brain.
Celluar localization	Nucleus;Plasma Membrane;
UniPort	O15394