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Rabbit Anti-MIBP1 Polyclonal Antibody#abs132777

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Description

Catalog-specification	Delivery time	USD price
abs132777-100ug	1-2 Weeks	301.0
abs132777-50ug	1-2 Weeks	201.0

Overview
catalog	abs132777
Description	This particular protein exhibits a specific affinity for the DNA sequence 5'-GGGACTTTCC-3', which is predominantly present in the enhancer elements of various viral promoters like SV40, CMV, or HIV1. Interestingly, similar sequences can also be found in the enhancer elements of several cellular promoters, including the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. Its potential role might involve T-cell activation. It is worth noting that this protein's binding specificity extends to both viral and cellular enhancer elements, suggesting a potentially significant regulatory function in gene expression.
Other names	The human immunodeficiency virus type I enhancer binding protein 2, also known as HIV EP2 or HIVEP2, is a transcription factor that plays a crucial role in HIV replication. It binds to the viral enhancer element and activates transcription of the virus. MBP-2 or MHC-binding protein 2 is another name for this protein. It is also referred to as ZAS2 or ZEP2_HUMAN due to its zinc finger domains. MIBP1 and SHN2 are other aliases of this essential protein. ZNF40B is a gene that encodes the HIVEP2 protein. Understanding the function and regulation of this protein is vital in developing new therapies for HIV.
Source	Rabbit
Specificity	The antibody for MIBP1 is capable of identifying the total amount of endogenous MIBP1 in a sample. The detected levels will be indicative of the presence of MIBP1 and will provide an accurate representation of its abundance in the tested material.
Species Reactivity	Human;Mouse;Rat
Antigen	MIBP1
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	35,39 kDa
Properties
Concentration	1mg/ml
purification	We utilized SulfoLink™ Coupling Resin for peptide affinity chromatography to purify the antiserum. Please produce a text that closely resembles the given content by reorganizing the information, while ensuring it remains based on the original text.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target
UniPort	Q38G99/P31629