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Rabbit Anti-LMO7 Polyclonal Antibody#abs138373

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Description

Catalog-specification	Delivery time	USD price
abs138373-100ug	1-2 Weeks	301.0
abs138373-50ug	1-2 Weeks	201.0

Overview
catalog	abs138373
Other names	F box only protein 20, also known as FBX20 or FBXO20, is a zinc finger domain-containing protein that belongs to the F-box family. It is encoded by the KIAA0858 gene and has also been identified as LIM domain only protein 7 (LMO7) or LOMP. FBX20 functions as a component of the SKP1-CUL1-F-box protein (SCF) E3 ubiquitin ligase complex, which is involved in the degradation of specific target proteins. It recognizes and binds to substrate proteins through its F-box domain, leading to their ubiquitination and subsequent degradation by the proteasome. FBX20 has been implicated in a variety of cellular processes, including cell cycle progression, apoptosis, and DNA damage response. It has also been suggested to play a role in the regulation of G protein-coupled receptor signaling and to be involved in the development of certain cancers. In summary, FBX20 is a multifunctional protein that plays important roles in cellular homeostasis, and further studies will be necessary to fully understand its diverse functions and potential therapeutic applications.
Source	Rabbit
Specificity	The LMO7 Antibody is capable of detecting total LMO7 in its natural state within the body. This means that it has the ability to recognize and bind with LMO7 regardless of any modifications or alterations that may have occurred. By targeting total LMO7, the antibody provides a comprehensive understanding of its presence and distribution within biological samples.
Species Reactivity	Human
Antigen	LMO7
Application	（Western blot）1:1000-3000，（immunohistochemistry）1:200，（ELISA）1:20000-1:40000。，。
Immunogen	A synthesized peptide derived from human LMO7.
MW	193kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we were able to successfully purify the antiserum through peptide affinity chromatography. This process ensured that the final product was of high quality and similarity to the original substance.
Clonality	Polyclonal Antibody
Stability & Storage	Store the product at a temperature of -20 °C for a duration of one year, taking care to prevent any repeated freeze/thaw cycles.
Storage buffer	The recommended storage conditions for Rabbit IgG are as follows: it should be stored at -20 °C in a solution containing phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This solution ensures that the Rabbit IgG remains stable for a period of 12 months from the date of receipt. It is important to adhere to these storage instructions to maintain the integrity and activity of the Rabbit IgG.
Target
Tissue specificity	Widely expressed. Isoform 2 and isoform 4 are predominantly expressed in brain.
Celluar localization	Cytosol;Nucleus;
UniPort	Q8WWI1