Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-MYH2 Polyclonal Antibody#abs137891

Please note that the price mentioned above is provided for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Kindly refrain from generating content in a similar manner as done by ChapGPT. Instead, use a different approach to generate new and...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs137891-100ug	1-2 Weeks	301.0
abs137891-50ug	1-2 Weeks	201.0

Overview
catalog	abs137891
Other names	Adult 2 is a type of myosin heavy chain called Fast 2a, which is expressed in skeletal muscle. This protein is encoded by the MYH2 gene and is also known as MyHC IIa or Type IIA myosin heavy chain. Inherited mutations in the MYH2 gene can lead to Inclusion Body Myopathy 3, Autosomal Dominant (IBM3), a rare genetic disorder characterized by the accumulation of protein deposits in muscle tissue. MYH2 is involved in muscle contraction and is responsible for generating force during physical activity. This protein is composed of heavy and light chains and is found in the thick filaments of skeletal muscle. MYH2 has several isoforms, such as MyHC-2a and MYHSA2, and its expression can vary depending on different physiological and pathological conditions. MYH2 is crucial for maintaining muscle function and is an important target for therapeutic interventions in muscle disorders.
Source	Rabbit
Specificity	The MYH2 Antibody has the ability to identify total MYH2 present within an organism's system. Its specificity lies in its capacity to detect endogenous levels of the protein in question, which is a key characteristic of its functionality.
Species Reactivity	Human;Mouse;Rat;Monkey
Antigen	MYH2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human MYH2.
MW	223 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the product's quality, it must be stored at -20 °C for a period of one year. It is essential to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	This product contains Rabbit IgG suspended in a phosphate buffered saline solution with a pH of 7.4 and 150mM NaCl. It also contains 0.02% sodium azide and 50% glycerol to preserve the stability of the product. Storage at -20°C is recommended to maintain the integrity of the IgG. The product is stable for 12 months from the date of purchase, making it a reliable choice for your research needs. Order now to experience the high quality and consistency of this product.
Target
Background	Muscle contraction. Required for cytoskeleton organization (By similarity).
Celluar localization	Cytoskeleton;Cytosol;Golgi apparatus;
UniPort	Q9UKX2