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Rabbit Anti-LIPC Polyclonal Antibody#abs135931

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Description

Catalog-specification	Delivery time	USD price
abs135931-100ug	1-2 Weeks	301.0
abs135931-50ug	1-2 Weeks	201.0

Overview
catalog	abs135931
Description	LIPC, also known as HTGL and HL, is a member of the AB hydrolase superfamily and Lipase family. It is capable of catalyzing the hydrolysis of phospholipids, mono-, di-, and triglycerides, as well as acyl-CoA thioesters. Significantly, LIPC plays a crucial role in the metabolism of HDL. Additionally, it exhibits a binding affinity towards heparin. For further details, kindly refer to the original text provided above.
Other names	Hepatic lipase, also known as hepatic triacylglycerol lipase or HL, is an important enzyme in the human body. It is also referred to as lipase member C, lipC, LIPC_HUMAN, and LIPH. This versatile enzyme is involved in lipid metabolism and plays a critical role in the breakdown and digestion of fats. HDLCQ12 is an identifier used to reference this particular lipase. It is essential to understand the functions and characteristics of hepatic lipase to appreciate its significance in various physiological processes. By examining its structure and activity, researchers have gained insights into its therapeutic potential in conditions such as dyslipidemia and atherosclerosis. Through further study, scientists aim to unlock the full potential of hepatic lipase as a target for therapeutic interventions and explore its role in maintaining lipid homeostasis. Overall, hepatic lipase emerges as a fascinating molecule with far-reaching implications in human health and disease.
Source	Rabbit
Specificity	The LIPC Antibody is capable of detecting total LIPC at its endogenous levels within an organism.
Species Reactivity	Human;Mouse;Rat
Antigen	LIPC
Application	We have different dilution ranges for our antibodies in various applications. For Western Blotting, the recommended dilution is 1:500-1:2000. In Immunohistochemistry, the dilution range is 1:50-1:200. For Immunofluorescence/Immunocytochemistry, the suggested dilution is 1:100-1:500. Lastly, for ELISA assays using peptide antigens, the dilution range is 1:20000-1:40000. These dilution ranges ensure optimal performance and reliable results for each specific application.
Immunogen	A synthesized peptide derived from human LIPC.
MW	56kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the peptide affinity chromatography process to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	One year storage is recommended at -20 °C to maintain product quality. It is important to avoid exposing the product to repeated freeze/thaw cycles.
Storage buffer	This solution contains rabbit IgG in a buffer of phosphate saline with pH 7.4, 150mM NaCl, and 0.02% sodium azide. It also contains 50% glycerol, which acts as a stabilizer, and must be stored at a temperature of -20°C. The solution is stable for a period of 12 months from the date of receipt, meaning it can be stored for an extended period without losing its efficacy or potency. This makes it an ideal solution for various laboratory applications. Overall, this solution is a reliable and effective reagent that can be used for a wide range of immunological applications. So, if you need a highly potent rabbit IgG solution, this is the perfect product for you!
Target
Background	Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;
UniPort	P11150