Rabbit Anti-AFP Polyclonal Antibody#abs131212

abs131212-50ug

1-2 Weeks

201

abs131212-100ug

1-2 Weeks

301

Description

Human AFP, also known as alpha-fetoprotein, exhibits strong binding affinity for copper, nickel, and fatty acids, surpassing its binding capability for serum albumin. However, its binding efficiency for bilirubin is relatively lower. It is worth noting that only a small fraction, less than 2%, of human AFP possesses the ability to bind to estrogen.

Other names

Alpha fetoprotein (AFP) or alpha fetoglobulin is a protein that is commonly referred to as AFPD or alpha fetoprotein precursor. It is also known as alpha-1-fetoprotein and is often abbreviated as FETA or FETA_HUMAN. This protein is associated with a medical condition called hereditary persistence of alpha fetoprotein (HPAFP).
HPAFP is a condition where there is a persistent presence of alpha fetoprotein in the blood. This condition is included in the various names associated with alpha fetoprotein. Alpha fetoprotein is primarily produced by the liver and yolk sac during fetal development. It plays a crucial role in the transportation of nutrients and protection of the developing fetus.
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Source

Rabbit

Specificity

The endogenous levels of total AFP can be accurately detected using the AFP Antibody.

Predictive reaction species

Pig;Dog;Horse

Application

The recommended dilution range for Western blotting is 1:500-1:2000, for immunohistochemistry is 1:50-1:200, and for ELISA using peptide is 1:20000-1:40000.

A synthesized peptide derived from human AFP.

Properties

1mg/ml

Purification

Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. To ensure optimal results, this process was carefully carried out to separate impurities from the antiserum, thereby obtaining a highly purified product.

Clonality

Polyclonal Antibody

To maintain the integrity of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated freeze/thaw cycles, as this can compromise the quality and effectiveness of the product. Therefore, it is essential to take measures to ensure that the product is properly stored and handled in order to optimize its lifespan and usefulness.

Storage buffer

The Rabbit IgG solution comes in a phosphate buffered saline with a pH of 7.4, 150mM NaCl and 0.02% sodium azide. It is also mixed with 50% glycerol and should be stored at a temperature of -20 °C. This solution is stable for up to 12 months once received.

Target

Background

Alpha-fetoprotein (AFP) is a protein that binds to copper, nickel, and fatty acids. Although it can bind to bilirubin, it is not as efficient as serum albumin. It is interesting to note that only a small fraction of human AFP, which is less than 2%, exhibits any estrogen-binding capabilities.

Tissue specificity

The production of plasma takes place in the fetal liver and yolk sac. These organs are responsible for synthesizing this essential component of blood. Plasma serves as a medium for carrying important nutrients, hormones, and other substances throughout the body. Its production during fetal development is critical for the proper growth and development of the fetus. Overall, plasma plays a vital role in maintaining the health and wellbeing of the body, and its synthesis by the liver and yolk sac is crucial for ensuring proper functioning.

Celluar localization

Cytosol;Endoplasmic reticulum;Extracellular region or secreted;

P02771