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Rabbit Anti-LGALS1 Polyclonal Antibody#abs137566

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Description

Catalog-specification	Delivery time	USD price
abs137566-100ug	1-2 Weeks	301.0
abs137566-50ug	1-2 Weeks	201.0

Overview
catalog	abs137566
Other names	One of the proteins in our body is the 14 kDa laminin-binding protein, also known as the 14 kDa lectin or beta galactoside-binding lectin. It is a beta-galactoside binding protein, also referred to as beta-galactoside-binding lectin L-14-I or galectin. Other names for this protein include galaptin, galbp, hbl, hlbp14, hpl, L 14.5, L-14.5, L14, lactose binding lectin 1, and lectin galactoside-binding soluble 1. Its gene is LGALS1, and it is also sometimes called LGALS 1 or LEG1_HUMAN. This protein is involved in many biological processes, including cell adhesion, cell proliferation, and apoptosis. It binds to different types of molecules, including carbohydrates, glycoproteins, and extracellular matrix proteins like laminin. It has been shown to play a role in cancer, inflammation, and immune response, and may be a potential target for disease treatments. The 14 kDa laminin-binding protein is found in many tissues throughout the body, including the heart, lungs, liver, and brain. It is also present in some cell types, such as white blood cells, epithelial cells, and endothelial cells. Studies have suggested that it may interact with other proteins and signaling pathways, including the MAPK pathway, which is involved in cell growth and differentiation. Overall, the 14 kDa laminin-binding protein is a versatile protein with many functions and potential roles in diseases. Further research is needed to fully understand its mechanisms and potential therapeutic applications.
Source	Rabbit
Specificity	Total LGALS1 levels can be detected by the LGALS1 Antibody, which is capable of recognizing endogenous levels of LGALS1. To provide a highly similar content, the rearranged version of the original text could be as follows: The LGALS1 Antibody is designed to identify and measure the overall levels of LGALS1 present within a biological system. It exhibits the ability to accurately detect the endogenous levels of LGALS1, allowing for comprehensive analysis of its expression.
Species Reactivity	Human;Mouse;Rat
Antigen	LGALS1
Application	WB1:1000-3000，IHC1:200，IF/ICC1:100-1:500，ELISA ()1:20000-1:40000。，。
Immunogen	A synthesized peptide derived from human LGALS1.
MW	15 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum. A highly similar content can be generated by rearranging the provided information in the original text.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage, it is recommended to store the product at a temperature of -20 °C for up to one year. It is important to take note and avoid any repeated freeze/thaw cycles as this may affect the quality of the product. Please keep in mind these storage guidelines to maintain the integrity of the product.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Tissue specificity	Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
Celluar localization	Cytosol;Endoplasmic reticulum;Extracellular region or secreted;Nucleus;
UniPort	P09382