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Rabbit Anti-PHLA1 Polyclonal Antibody#abs140705

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Description

Catalog-specification	Delivery time	USD price
abs140705-100ug	1-2 Weeks	301.0
abs140705-50ug	1-2 Weeks	201.0

Overview
catalog	abs140705
Other names	There are several names associated with the gene that encodes for the protein known as apoptosis associated nuclear protein. These include PHLDA1, PHRIP, Tdag, and TDAG51 among others. The protein is involved in programmed cell death or apoptosis and contains proline and glutamine-rich domains. It also has a pleckstrin homology-like domain. The protein is known to play a role in the regulation of cancer cell growth, and mutations in the gene have been linked to certain types of cancer. Overall, the function of apoptosis associated nuclear protein remains an area of active research, but its potential as a therapeutic target for cancer treatment is exciting.
Source	Rabbit
Specificity	The total levels of endogenous PHLA1 can be detected using the PHLA1 Antibody. To produce related content, the original text information must be rearranged.
Species Reactivity	Human;Mouse;Rat
Antigen	PHLA1
Application	For Western Blot analysis, the recommended dilution range is 1:500 to 1:1000. When performing Immunofluorescence or Immunocytochemistry, it is suggested to use a dilution range of 1:100 to 1:500. For Enzyme-Linked Immunosorbent Assay (ELISA) using peptide antigens, the optimal dilution range is 1:20000 to 1:40000. These dilution ranges ensure accurate and reliable results in various applications.
Immunogen	A synthesized peptide.
MW	40 KD
Properties
Concentration	1mg/ml
purification	We utilized SulfoLink™ Coupling Resin to perform peptide affinity chromatography, effectively purifying the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is advised to keep it at a temperature of -20 °C for up to one year. However, it is essential to avoid freeze/thaw cycles, as it can affect the stability of the product. Therefore, it is crucial to store the product properly to ensure its efficacy and safety.
Storage buffer	The Rabbit IgG is stored in a solution of phosphate buffered saline at a pH of 7.4. The solution contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C and is stable for a period of 12 months from the date of receipt.
Target
Background	Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.
Tissue specificity	Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).
Celluar localization	Cytosol;Nucleus;
UniPort	Q8WV24