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Rabbit Anti-LEG7 Polyclonal Antibody#abs131396

Description

Catalog-specification	Delivery time	USD price
abs131396-100ug	1-2 Weeks	301.0
abs131396-50ug	1-2 Weeks	201.0

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Overview
catalog	abs131396
Description	Normal growth control requires the involvement of cell-cell and/or cell-matrix interactions. This process involves a pro-apoptotic protein that operates within cells prior to activating JNK and releasing cytochrome c. These interactions are essential for maintaining cellular function and ensuring proper regulation of growth.
Other names	Galectin 7 (Gal-7), also known as HKL-14 or keratinocyte lectin 14, is a protein encoded by the LGALS7 gene in humans. It belongs to the galectin family of proteins, which are known for their ability to bind to specific sugar molecules. Galectin 7 is expressed in many tissues, including the skin, where it plays a role in regulating cell growth and differentiation. Galectin 7 has been shown to have a diverse range of functions. It has been implicated in the regulation of cell cycle progression, apoptosis, and inflammation. Galectin 7 has also been reported to act as a tumor suppressor, with its expression frequently being lost in various types of cancer. Galectin 7 is regulated by the tumor suppressor protein p53, with its expression being induced in response to DNA damage. As a result, galectin 7 is sometimes referred to as the p53-induced gene 1 protein (PIG1). Galectin 7 has been suggested as a potential biomarker for cancer diagnosis and prognosis, and it may also have therapeutic potential in cancer treatment.
Source	Rabbit
Specificity	The LEG7 antibody is capable of detecting the natural levels of total LEG7 present in an organism. By rearranging the wording, the following content is generated: The endogenous levels of total LEG7 can be effectively identified using the LEG7 Antibody.
Species Reactivity	Human;Mouse;Rat
Antigen	LEG7
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human LEG7.
MW	15 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography with SulfoLink™ Coupling Resin was utilized to purify the antiserum. Let me provide you with a rephrased version of the content while maintaining its original meaning.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the integrity of the product, it is recommended that it be stored at a temperature of -20 °C for a period of one year. It is advised to avoid subjecting the product to frequent freeze/thaw cycles as this may alter its properties.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
Tissue specificity	Mainly expressed in stratified squamous epithelium.
Celluar localization	Extracellular region or secreted;Nucleus;
UniPort	P47929