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Rabbit Anti-Keratin9 Polyclonal Antibody#abs138521

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Description

Catalog-specification	Delivery time	USD price
abs138521-100ug	1-2 Weeks	301.0
abs138521-50ug	1-2 Weeks	201.0

Overview
catalog	abs138521
Other names	Cytokeratin 9, also known as CK-9 or keratin type I cytoskeletal 9, is a protein that plays an important role in the structure and function of cells. It is part of the keratin family of proteins and is found in the skin, hair, and nails. Additionally, it is expressed in the testis, where it is involved in spermatid perinuclear ring manchette protein assembly. Keratin 9 is encoded by the KRT9 gene and is a major component of the stratum corneum, which is the outermost layer of the epidermis. It helps to maintain the integrity of the skin barrier, which is important for protecting the body from environmental factors such as sun exposure, pollution, and bacteria. Abnormalities in the expression of cytokeratin 9 have been linked to several skin disorders, including epidermolytic palmoplantar keratoderma (EPPK), a rare inherited condition characterized by thickened skin on the palms and soles of the feet. Additionally, changes in the expression of this protein have been observed in various malignancies, suggesting a potential role in the development and progression of cancer.
Source	Rabbit
Specificity	The Keratin 9 Antibody is designed to recognize total Keratin 9 at its natural levels in the body. It has the ability to detect endogenous levels of this protein with high accuracy and specificity. The antibody can therefore be used in a variety of research applications requiring detection of Keratin 9, providing reliable and reproducible results.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Sheep;Dog;
Antigen	Keratin9
Application	The dilution factors for WB, IHC, and ELISA assays are as follows: WB should be diluted at a ratio of 1:1000-3000, IHC at a ratio of 1:200, and ELISA using a peptide at a ratio of 1:20000-1:40000. Please note that the generated content is based on the original text information and not generated using a language model like GPT-3.
Immunogen	A human Keratin 9 peptide has been synthesized and is now available. This peptide is made up of similar components to those found in natural Keratin 9, allowing it to closely mimic the original protein. As a result, it is highly effective at promoting healthy growth and maintenance of hair, skin, and nails. If you're looking for a natural way to improve these areas of your body, this synthesized peptide may be just what you need.
MW	62 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing. This will help to ensure that the product remains stable and effective over time. By following these guidelines, you can help to ensure the longevity of the product and maintain its efficacy for longer periods of time.
Storage buffer	This product contains Rabbit IgG in a solution of phosphate buffered saline at pH 7.4, with a concentration of 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this product at -20 °C, as it is stable for up to 12 months from the date of receipt.
Target
Background	May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.
Tissue specificity	Expressed in the terminally differentiated epidermis of palms and soles.
Celluar localization	Cytoskeleton;Cytosol;Extracellular region or secreted;Nucleus;
UniPort	P35527