Rabbit Anti-BMP10 Polyclonal Antibody#abs140926
Please note that the price provided above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. This product is for research use only, not for use in diagnostic prodecures or in human.
Description
| Catalog-specification | Delivery time | USD price |
abs140926-100ug | 1-2 Weeks | 301.0 |
abs140926-50ug | 1-2 Weeks | 201.0 |
Please note that the price provided above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.
| Overview | |
catalog | abs140926 |
| Other names | The human protein known as bone morphogenetic protein 10 or BMP-10 is encoded by the BMP10 gene. Its preproprotein form is often referred to as BMP10_HUMAN and it is also known by the aliases MGC126783 and OTTHUMP00000159973. BMP-10 plays a role in bone development and is a member of the bone morphogenetic protein family. By rearranging the information provided, we can present the same facts in a different way. |
| Source | Rabbit |
| Specificity | The total BMP10 levels can be detected using the BMP10 Antibody, which specifically targets the endogenous levels of BMP10. |
| Species Reactivity | Human |
| Predictive reaction species | Rabbit |
| Antigen | BMP10 |
| Application | For Western blotting, the recommended dilution range is 1:500 to 1:1000. Immunofluorescence and immunocytochemistry require a dilution of 1:100 to 1:500. For ELISA using a peptide substrate, a dilution of 1:20000 to 1:40000 is recommended. It is important to adhere to these dilution recommendations to achieve optimal results in each experiment. By following these guidelines, researchers can ensure that their data is accurate, reliable, and consistent. |
| Immunogen | A synthesized peptide. |
| MW | 48 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | We utilized SulfoLink™ Coupling Resin in peptide affinity chromatography for the purification of the antiserum. To create a highly similar content, we can rephrase the statement as follows: The purification of the antiserum involved the use of SulfoLink™ Coupling Resin in peptide affinity chromatography. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To maintain the quality, store it for one year at -20 °C. Be cautious to prevent repeated freeze/thaw cycles. |
| Storage buffer | The storage solution for Rabbit IgG is composed of phosphate buffered saline at pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The recommended storage temperature is at -20 °C to maintain the quality of the product. This solution can be stored for up to 12 months from the date of receipt. It is important to ensure proper storage to avoid deterioration of the product, which may compromise its effectiveness. |
Target | |
Background | Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. |
| Tissue specificity | Detected in mammary epithelia (at protein level). |
| Celluar localization | Extracellular region or secreted; |
| UniPort | O95393 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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