Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-IL19 Polyclonal Antibody#abs138502

Please note that the price mentioned above is only provided as a reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis IL19 using HeLa whole cell lysates This product is for research use only, not for use in diagnostic...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs138502-100ug	1-2 Weeks	301.0
abs138502-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only provided as a reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs138502
Other names	IL-10C is also known as IL-19 or Interleukin 19. IL-19 is a protein encoded by the IL19 gene in humans. It is also referred to as IL19_HUMAN, MDA1, NG.1, or ZMDA1. IL-19 is a member of the interleukin-10 (IL-10) cytokine family and plays a role in modulating immune responses. IL-19 is closely related to IL-20 and IL-24, as they all share a similar gene structure. It is secreted by activated monocytes and myeloid dendritic cells. IL-19 binds to the IL-20 receptor complex, which consists of IL-20 receptor 1 and IL-20 receptor 2. The binding of IL-19 to its receptors activates the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway. This leads to the activation of downstream targets, including STAT3. IL-19-induced STAT3 activation is involved in regulating immune responses and inflammation. IL-19 has been implicated in various pathological conditions, including autoimmune diseases, cancer, and inflammatory disorders. It was initially identified as a melanoma differentiation-associated protein-like protein (MDA1), indicating its potential involvement in melanoma development and progression. Overall, IL-19 is an important cytokine involved in immune regulation and inflammation. Further research is needed to elucidate its precise role in different disease contexts and explore its potential as a therapeutic target.
Source	Rabbit
Specificity	The IL19 Antibody is capable of detecting total IL19 levels that are present naturally in the body. This means that the antibody is able to recognize the IL19 protein that is produced by the body, without any external interference.
Species Reactivity	Human
Antigen	IL19
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human IL19.
MW	20 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography purification. Reorganization of the original text information has led to the creation of a highly similar content that conveys the same meaning.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting it to multiple freeze/thaw cycles as this may have an adverse effect on its stability and efficacy. Ensure that proper storage conditions are maintained at all times to maximize the shelf life of the product.
Storage buffer	This Rabbit IgG is provided in a solution of phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide and 50% glycerol, and should be stored at -20 °C. It is stable for a period of 12 months from the date of receipt.
Target
Background	Inducing apoptosis, up-regulating IL-6 and TNF-alpha, and playing significant roles in inflammatory responses are some essential functions that May performs. These functions were determined based on the similarity observed in the original text.
Celluar localization	Extracellular region or secreted;
UniPort	Q9UHD0