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Rabbit Anti-HORMAD1 Polyclonal Antibody#abs140442

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Description

Catalog-specification	Delivery time	USD price
abs140442-100ug	1-2 Weeks	301.0
abs140442-50ug	1-2 Weeks	201.0

Overview
catalog	abs140442
Other names	CT46, also known as cancer/testis antigen CT46, is a protein that contains the HORMA domain. It is also referred to as HORMA domain containing protein 1 or simply HORMA domain containing protein. Additionally, it is also called the newborn ovary HORMA protein or NOHMA. Other names include OTTHUMP00000032933, RP11-363I22 1, and Testis tissue sperm binding protein Li 86P.
Source	Rabbit
Specificity	The total HORMAD1 levels can be detected using the HORMAD1 Antibody, which specifically targets the endogenous HORMAD1 protein.
Species Reactivity	Human;Mouse
Predictive reaction species	Rabbit;Bovine;Dog
Antigen	HORMAD1
Application	The suggested dilutions for Western Blot (WB) are 1:1000, for Immunofluorescence (IF) and Immunocytochemistry (ICC) are 1:100-1:500, and for Enzyme-Linked Immunosorbent Assay (ELISA) using peptide are 1:20000-1:40000. It is important to follow these dilution guidelines to obtain accurate and reliable results.
Immunogen	A synthesized peptide derived from human HORMAD1.
MW	45kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. Our goal was to ensure that the resulting antiserum was of the highest quality and similarity possible. This process involved careful separation and purification of peptides in order to create a highly effective antiserum that is useful in a variety of applications. The SulfoLink™ Coupling Resin was instrumental in facilitating this process and ensuring that the antiserum is of the highest possible quality.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the product is stored at a temperature of -20 °C for a period of one year. It is important to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	This product contains rabbit IgG suspended in a solution of phosphate buffered saline at a pH of 7.4, with 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. To ensure maximum effectiveness, it is recommended to store this product at -20°C. This solution remains stable for up to 12 months after its initial receipt.
Target
Background	Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
Tissue specificity	Testis-specific. Over-expressed in carcinomas.
Posttranslational modification	Phosphorylated at Ser-377 in a SPO11-dependent manner.
Celluar localization	Nucleus;
UniPort	Q86X24