Rabbit Anti-HMMR Polyclonal Antibody#abs135111

Rabbit Anti-HMMR Polyclonal Antibody#abs135111

Please note that the price provided is only for your reference. For more detailed information on pricing, please get in touch with our seller, Vecent. Western blot analysis of extracts from HepG2 cells, using HMMR antibody. This product is for research use only, not for use in diagnostic...

Description

Catalog-specificationDelivery timeUSD price

abs135111-50ug

1-2 Weeks

201.0

abs135111-100ug

1-2 Weeks

301.0

Please note that the price provided is only for your reference. For more detailed information on pricing, please get in touch with our seller, Vecent.


Overview

catalog

abs135111
Other namesThe CD168 antigen, also known as HMMR or Hyaluronan-mediated motility receptor, is an intracellular hyaluronic acid-binding protein. It is also referred to as RHAMM, IHABP, or Receptor for hyaluronan-mediated motility. Other names for this protein include MGC119494 and MGC119495. The gene associated with CD168 is OTTHUMP00000196920. This protein is involved in hyaluronan-mediated motility and plays a role in various cellular processes.
SourceRabbit
SpecificityThe HMMR antibody is capable of identifying total HMMR levels that exist naturally within the body. To create similar content based on this information, one could say that the HMMR antibody detects the presence of endogenous HMMR proteins at their total levels.
Species ReactivityHuman
AntigenHMMR
ApplicationThe dilution ranges for WB are 1:500~1:1000, for IHC are 1:50~1:200, for IF/ICC are 1:100-1:500, and for ELISA (peptide) are 1:20000-1:40000. You can adjust the dilutions accordingly to optimize your experimental conditions.
ImmunogenA synthesized peptide.
MW85 KD
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography.
ClonalityPolyclonal Antibody
Stability & StorageTo ensure the preservation of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to multiple cycles of freezing and thawing.
Storage bufferThe storage conditions for rabbit IgG are as follows: it should be stored at a temperature of -20 °C. The IgG is formulated in phosphate buffered saline with a pH of 7.4. Additionally, the solution contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that this product is stable for a period of 12 months from the date of receipt.

Target

Background

Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.

Tissue specificityExpressed in breast cancer cell lines and in normal breast tissue.
Celluar localizationCytosol;Plasma Membrane;
UniPortO75330


Western blot analysis of extracts from HepG2 cells, using HMMR antibody.

This product is for research use only, not for use in diagnostic prodecures or in human.


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