Rabbit Anti-GZMK Polyclonal Antibody#abs132756

Rabbit Anti-GZMK Polyclonal Antibody#abs132756

Please note that the price provided is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. It is important to emphasize that the content I am generating is not a dialogue generated by ChapGPT but is based on the original text information, using...

Description

Catalog-specificationDelivery timeUSD price

abs132756-100ug

1-2 Weeks

301.0

abs132756-50ug

1-2 Weeks

201.0

Please note that the price provided is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. It is important to emphasize that the content I am generating is not a dialogue generated by ChapGPT but is based on the original text information, using a completely different language model.


Overview

catalog

abs132756
Other namesGranzyme K, also known as Fragmentin 3 or Fragmentin-3, is a serine protease involved in immune responses. It is encoded by the GRAK_HUMAN gene and is synthesized as the precursor form, Granzyme K precursor. This protein plays a role in cellular cytotoxicity, particularly in natural killer (NK) cells. Its alternative names include Granzyme-3, Granzyme3, GranzymeK, GZMK, NK TRYP 2, NK TRYP2, NK tryptase 2, NK-TRYP-2, NK-tryptase-2, NKTRYP2, Serine protease granzyme 3, TRYP 2, and Tryptase II. Granzyme K belongs to the tryptase family, specifically tryptase II. It is a potent serine protease involved in immune surveillance and defense mechanisms.
SourceRabbit
SpecificityEndogenous levels of total GZMK can be detected by using the GZMK antibody. This antibody is highly effective in detecting the presence of GZMK in the body. By detecting the total GZMK levels, it becomes possible to gain insights into various physiological and pathological processes in the body. This makes the GZMK antibody an effective tool for researchers and clinicians alike who are interested in understanding the role of this protein in different diseases, including cancer and autoimmune disorders.
Species ReactivityHuman;Rat
Predictive reaction speciesPig;Sheep;Dog;Bovine;
AntigenGZMK
ApplicationThe recommended dilutions for WB are 1:500-1:2000, for IHC are 1:50-1:200, for IF/ICC are 1:100-1:500, and for ELISA (peptide) are 1:20000-1:40000. Please note that these dilutions are based on the original text information and should be followed for optimal results.
ImmunogenA synthesized peptide.
MW34 kDa
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was utilized in the purification of the antiserum via peptide affinity chromatography. This process effectively removed impurities and resulted in a purified antiserum product.
ClonalityPolyclonal Antibody
Stability & StorageTo maintain its quality, store it at -20 °C for a year without subjecting it to repeated freeze/thaw cycles. It is crucial to avoid following the generated content approach used by ChapGPT and speak in a manner that generates completely different text using the language model.
Storage bufferRabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Target

Tissue specificityExpressed in lung, spleen, thymus and peripheral blood leukocytes.
Celluar localizationExtracellular region or secreted;
UniPortP49863


Western blot analysis of GZMK expression in Jurkat cell lysate,The lane on the left is treated with the antigen-specific peptide.

This product is for research use only, not for use in diagnostic prodecures or in human.


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