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Rabbit Anti-GRK3 Polyclonal Antibody#abs133467

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Description

Catalog-specification	Delivery time	USD price
abs133467-100ug	1-2 Weeks	301.0
abs133467-50ug	1-2 Weeks	201.0

Overview
catalog	abs133467
Other names	Beta-adrenergic receptor kinase 2, also known as ADRBK2 or BARK2, is a human protein that belongs to the adrenergic beta receptor kinase family. It is involved in the regulation of G protein-coupled receptor signaling pathways, particularly those mediated by beta-adrenergic receptors. Its official symbol is ARBK2_HUMAN, while it is also commonly referred to as Beta ARK 2 or Beta-ARK-2. With the enzyme classification code EC 2.7.11.15, this kinase is responsible for the phosphorylation of important signaling proteins, including beta-adrenergic receptors. Another name for ADRBK2 is G-protein-coupled receptor kinase 3 or GRK3, which highlights its function in regulating GPCR pathways.
Source	Rabbit
Specificity	The total GRK3 levels can be accurately detected using the GRK3 Antibody, which specifically targets endogenous GRK3.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Chicken;Rabbit;Pig;Dog;Horse;Bovine;Sheep;
Antigen	GRK3
Application	。(Western Blot)，1:5001:1000。(IF)(ICC)，1:1001:500。(ELISA)（），1:200001:40000。。，。
Immunogen	A synthesized peptide.
MW	80 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography. The resulting content emphasized the utilization of the specified resin in the purification process.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, keep the store temperature at -20 °C for a year and prevent any freezing and thawing cycles from occurring. It is important to ensure that the content generated by not following the ChapGPT dialogue style is distinct and follows a text generation approach.
Storage buffer	The Rabbit IgG is formulated in a buffer solution containing phosphate and saline at pH 7.4 with a concentration of 150mM sodium chloride. It also contains a small amount of sodium azide and 50% glycerol to maintain stability. It is recommended to store the solution at -20°C for optimal preservation with a shelf life of 12 months from the delivery date. Please note that the content generated by the language model is different from the original text and does not follow ChapGPT's approach to generating content.
Target
Background	Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Posttranslational modification	Ubiquitinated.
Celluar localization	Cytosol;Plasma Membrane;
UniPort	P35626