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Rabbit Anti-GluR8 Polyclonal Antibody#abs131564

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Description

Catalog-specification	Delivery time	USD price
abs131564-100ug	1-2 Weeks	301.0
abs131564-50ug	1-2 Weeks	201.0

Overview
catalog	abs131564
Description	The inhibition of adenylate cyclase activity is mediated by a G-protein, which serves as the receptor for glutamate function. A receptor that responds to glutamate activity involves a G-protein that effectively inhibits the activity of adenylate cyclase.
Other names	Glutamate receptor metabotropic 8, also known as GRM8 or mGluR8, is encoded by the FLJ41058 gene and is classified as a GPRC1H protein. Metabotropic glutamate receptor 8 is another name used to refer to this receptor. Additionally, it is sometimes designated as MGC126724. It plays a critical role in the metabotropic signaling pathways associated with glutamate receptors.
Source	Rabbit
Specificity	The mGluR8 Antibody has the ability to identify the existing amounts of total mGluR8 within the body. It is capable of detecting and recognizing the endogenous levels of the protein with precision and accuracy.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Pig;Dog;Horse;
Antigen	GluR8
Application	The dilutions for western blotting range from 1:500 to 1:2000, for immunohistochemistry they range from 1:50 to 1:200, and for ELISA using peptides, the dilutions range from 1:20000 to 1:40000. It is important to select the appropriate dilution for each application to ensure accurate and reliable results. Proper dilution allows for optimal detection of the target protein or peptide of interest while minimizing background signal.
Immunogen	A synthesized peptide derived from human mGluR8.
MW	102 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography to achieve purification.
Clonality	Polyclonal Antibody
Stability & Storage	Please make sure to store it at -20 °C for a duration of one year without subjecting it to repeated freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Celluar localization	Plasma Membrane;
UniPort	O00222