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Rabbit Anti-GLP2R Polyclonal Antibody#abs139736

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Description

Catalog-specification	Delivery time	USD price
abs139736-100ug	1-2 Weeks	301.0
abs139736-50ug	1-2 Weeks	201.0

Overview
catalog	abs139736
Other names	The GLP-2 receptor, also known as GLP2R or glucagon-like peptide 2 receptor, plays a crucial role in regulating digestive function. This receptor is primarily found in the intestines and is activated by the hormone GLP-2, which stimulates the growth and repair of intestinal cells. Understanding the functions of the GLP-2 receptor has important implications for the treatment of gastrointestinal diseases such as inflammatory bowel disease. The protein encoded by the GLP2R gene, which is also referred to as GLP2R_HUMAN, is involved in transducing the signal from GLP-2 binding to the receptor into a cellular response. Therefore, this receptor is a promising target for pharmacological intervention. Overall, an in-depth knowledge of the GLP-2 receptor is crucial for developing new therapeutic strategies to combat digestive disorders.
Source	Rabbit
Specificity	The total GLP2R levels can be accurately measured using the GLP2R Antibody, which specifically recognizes the endogenous form of GLP2R. By utilizing this antibody, researchers can detect and analyze the overall expression levels of GLP2R in various biological samples.
Species Reactivity	Human;Rat;Monkey
Predictive reaction species	Chicken;Dog;
Antigen	GLP2R
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human GLP2R.
MW	63 kDa
Properties
Concentration	1mg/ml
purification	In order to purify the antiserum, the researchers utilized SulfoLink™ Coupling Resin for peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is advised to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles.
Storage buffer	The rabbit IgG is stored in a solution of phosphate buffered saline at pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, and should be kept at a temperature of -20 °C. It has a shelf life of 12 months from the date of receipt and is stable during this time.
Target
Background	This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Celluar localization	Plasma Membrane;
UniPort	O95838