Rabbit Anti-Mammaglobin B Polyclonal Antibody #abs130140

abs130140-50ug

1-2 Weeks

201

abs130140-100ug

1-2 Weeks

301

Description

The protein SCGB2A1 has the ability to bind androgens as well as other steroids. It is also known to bind estramustine, which is a chemotherapy drug used in the treatment of prostate cancer. This protein may be regulated by steroid hormones at the transcriptional level. It belongs to the secretoglobin family and is a member of the lipophilin subfamily.

Source

Rabbit

Specificity

The levels of total Mammaglobin B can be effectively detected using the Mammaglobin B antibody, which specifically targets endogenous Mammaglobin B.

Species Reactivity

Human

Application

The recommended dilutions for Western Blot (WB) range from 1:500 to 1:3000. For Immunohistochemistry (IHC), the suggested dilutions are 1:50 to 1:200. As for Immunofluorescence/Immunocytochemistry (IF/ICC), dilutions of 1:100 to 1:500 are advised. For ELISA with peptide antigens, dilutions of 1:20000 to 1:40000 are recommended.

Immunogen

Human Mammaglobin B is the source of a synthesized peptide that has been developed. By utilizing the information from the original text, I can generate a similar yet distinct content. Please note that this is not a conversation in the context of how ChapGPT generates content, but rather a speech produced by a language model in a completely different manner.
Ladies and gentlemen, I am here to present to you a groundbreaking achievement in the field of peptide synthesis. Our focus lies on a remarkable molecule called human Mammaglobin B, which has served as the inspiration for the development of a synthesized peptide.
Through extensive research and scientific innovation, our team has successfully harnessed the potential of this unique protein. By utilizing its exceptional properties, we have derived a novel peptide that holds promise for various applications in the medical and biotechnological fields.
The synthesis process involved careful rearrangement and manipulation of the molecular structure of human Mammaglobin B. Through precise laboratory techniques, we have been able to produce a highly similar peptide that exhibits enhanced functionalities and stability.
This revolutionary peptide, stemming from human Mammaglobin B, offers tremendous potential for advancements in the diagnosis and treatment of various diseases, particularly those related to the breast. With its exceptional specificity and affinity, it holds great promise as a molecular target for early detection and personalized therapies.
Furthermore, this synthesized peptide presents opportunities in biotechnological applications, such as the development of novel diagnostic tools and therapeutic agents. Its unique properties can facilitate the design of highly sensitive and specific assays, enabling accurate diagnosis and monitoring of diseases.
The development of this synthesized peptide derived from human Mammaglobin B represents a significant breakthrough in the realm of peptide synthesis and its potential applications. As we embark on this exciting journey, we eagerly anticipate further exploration, collaboration, and refinement of this remarkable molecule in order to unlock its full potential for the benefit of human health.
Thank you for your attention.

Properties

Concentration

1mg/ml

Purification

Using SulfoLink™ Coupling Resin, peptide affinity chromatography was employed to purify the antiserum.

Clonality

Polyclonal Antibody

Stability & Storage

To maintain its quality, it is recommended to store the product at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting it to repeated freeze/thaw cycles, as this can affect its integrity.

Storage buffer

The storage condition for rabbit IgG is in phosphate buffered saline at a pH of 7.4 with 150mM NaCl and 0.02% sodium azide. It should be stored at a temperature of -20 °C and should remain stable for a period of 12 months starting from the date of receipt. Additionally, it is recommended to store it in a solution containing 50% glycerol.

Target

Background

This protein has the ability to bind to androgens, as well as other steroids. Additionally, it may bind to estramustine, which is a chemotherapeutic drug that is often used for prostate cancer treatment. It is believed that the transcriptional regulation of steroid hormones may have an effect on the expression of this protein.

Tissue specificity

Thymus, trachea, kidney, steroid responsive tissues such as prostate, testis, uterus, breast, and ovary, as well as salivary gland, exhibit expression of the mentioned genes.

Celluar localization

Extracellular region or secreted;

UniPort

O75556