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Rabbit Anti-GCNT4 Polyclonal Antibody#abs138788

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Description

Catalog-specification	Delivery time	USD price
abs138788-100ug	1-2 Weeks	301.0
abs138788-50ug	1-2 Weeks	201.0

Overview
catalog	abs138788
Other names	There are various names for the same enzyme: Core 2 (beta-1,6-N-acetylglucosaminyltransferase), Core 2 branching enzyme 3, Core2 GlcNAc transferase 3, GCNT4, and Glucosaminyl (N-acetyl) transferase 4. This glycosyltransferase enzyme is responsible for catalyzing the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to the galactose residue of a core 1 O-glycan, which results in the formation of a Core 2 structure on O-glycans. This process is crucial for numerous biological functions, including cell adhesion, signaling, and immune recognition. Despite having multiple names, this enzyme is highly specific and essential for the proper functioning of various biological systems.
Source	Rabbit
Specificity	The endogenous levels of total GCNT4 can be detected using the GCNT4 Antibody.
Species Reactivity	Human;Mouse
Antigen	GCNT4
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human GCNT4.
MW	53kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. A highly similar content can be expressed by rearranging the original text information.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to keep the product at a temperature of -20 °C for a period of one year. However, it is important to avoid subjecting the product to repeated freeze and thaw cycles, as this can compromise its stability and effectiveness over time. By following these storage guidelines, you can ensure that your product remains viable and ready for use whenever you need it.
Storage buffer	This product contains Rabbit IgG suspended in a solution of phosphate buffered saline at pH 7.4. The solution also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this product at a temperature of -20 °C for optimal stability. The product is expected to maintain its performance for up to 12 months from the date of receipt.
Target
Background	The core 2 O-glycan branching glycosyltransferase is an essential enzyme involved in the biosynthesis of mucin-type molecules. It plays a crucial role in facilitating the branching of core 2 O-glycans. However, it does not possess any activity related to core 4 O-glycans or I-branching.
Tissue specificity	Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node.
Celluar localization	Golgi apparatus;
UniPort	Q9P109