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Rabbit Anti-FucT-IV Polyclonal Antibody#abs138067

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Description

Catalog-specification	Delivery time	USD price
abs138067-100ug	1-2 Weeks	301.0
abs138067-50ug	1-2 Weeks	201.0

Overview
catalog	abs138067
Other names	Fucosyltransferase is an enzyme that plays a crucial role in many biological processes. One specific type of fucosyltransferase, known as alpha-3-fucosyltransferase (3-FAL), is responsible for adding fucose molecules to various substrates. This enzyme is also referred to by different names, including ELAM 1 ligand and ELAM ligand fucosyltransferase. It is involved in the synthesis of ELAM-1 ligands, which are important molecules in the immune response. Another name for alpha-3-fucosyltransferase is ELFT or FCT3A. It is also known as FUC-TIV or fucosyltransferase IV. This particular fucosyltransferase is myeloid-specific, meaning it is primarily expressed in myeloid cells. Alpha-3-fucosyltransferase, also called FUTIV or galactoside 3-L-fucosyltransferase, is responsible for adding fucose residues to glycoproteins and glycolipids. It is involved in the synthesis of Lewis X antigen, also known as LeX, which is an important carbohydrate structure involved in cell adhesion and signaling. Interestingly, alpha-3-fucosyltransferase is also associated with SSEA-1 (stage-specific embryonic antigen 1), which is a marker for embryonic stem cells. This suggests a potential role for this enzyme in embryonic development. In summary, alpha-3-fucosyltransferase is a versatile enzyme involved in various biological processes, including immune response, cell adhesion, and embryonic development. Its diverse names reflect its multiple functions and importance in different biological contexts.
Source	Rabbit
Specificity	The FucT-IV Antibody is capable of detecting the entirety of FucT-IV present within the body. This detection system targets natural levels of FucT-IV. To create a similar content, the original text's information must be rearranged.
Species Reactivity	Human;Mouse;Rat
Antigen	FucT-IV
Application	The recommended dilutions for Western blot are 1:1000-3000, for Immunohistochemistry it is 1:200, and for ELISA using peptide it ranges from 1:20000-1:40000. It is important to follow these dilutions in order to ensure accurate results in your experiments. For example, using a higher or lower dilution may result in overly intense or weak staining or signal in your assay. Therefore, it is crucial to optimize your dilution for each antibody in order to obtain the best possible results.
Immunogen	A synthesized peptide derived from human FucT-IV.
MW	45 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent the process of peptide affinity chromatography to achieve purification.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the storage temperature remains at -20 °C for a duration of one year to maintain the product's quality. It is crucial to prevent the occurrence of multiple freeze/thaw cycles.
Storage buffer	The provided content describes Rabbit IgG stored in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store it at -20 °C, and it remains stable for 12 months from the date of receipt. Rabbit IgG is stored in a solution of phosphate buffered saline, with a pH of 7.4. The solution contains 150mM NaCl, along with 0.02% sodium azide and 50% glycerol. It is advised to keep the stored solution at a temperature of -20 °C. It is worth noting that the stability of this solution is guaranteed for a period of 12 months from the date of receipt.
Target
Background	May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Celluar localization	Golgi apparatus;
UniPort	P22083