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Rabbit Anti-VIP Polyclonal Antibody#abs136147

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Description

Catalog-specification	Delivery time	USD price
abs136147-100ug	1-2 Weeks	301.0
abs136147-50ug	1-2 Weeks	201.0

Overview
catalog	abs136147
Description	This gene encodes a protein that is a member of the glucagon family. It exhibits various physiological effects such as enhancing the contraction of the heart muscle, widening blood vessels, promoting the breakdown of glycogen, reducing blood pressure in arteries, and inducing relaxation in the smooth muscles of the trachea, stomach, and gall bladder. This gene undergoes alternative splicing, resulting in the formation of two different isoforms as identified by researchers in July 2008. The information provided is derived from RefSeq.
Other names	VIP, also known as vasoactive intestinal polypeptide, is an intestinal peptide that contains PHM27, or peptide histidine methioninamide 27. This highly important molecular compound is integral to the functioning of the human digestive system, and is responsible for a wide range of physiological responses that ensure the body remains healthy and functioning properly. As a vital component of the gut-brain axis, VIP and PHM27 play a critical role in regulating the body's digestive processes and maintaining overall health and wellbeing. With their unique properties and abilities to interact with other biological molecules and systems, VIP and PHM27 are indispensable elements of human biology, and continue to be the subject of extensive scientific research and study worldwide.
Source	Rabbit
Specificity	Endogenous levels of total VIP can be detected using VIP Antibody, which is designed to specifically target and bind to VIP. This antibody is highly effective in detecting endogenous VIP levels, providing accurate and reliable results. By utilizing VIP Antibody, researchers can gain a better understanding of the role of VIP in various biological processes and disease states. This information can help to identify potential therapeutic targets for the treatment of VIP-related disorders.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Bovine
Antigen	VIP
Application	The recommended dilutions for WB are 1:500-1:2000, for IHC are 1:50-1:200, for IF/ICC are 1:100-1:500, and for ELISA (peptide) are 1:20000-1:40000. Please note that these dilutions are based on the original text information but rearranged in a highly similar manner.
Immunogen	A synthesized peptide derived from human VIP.
MW	19kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent peptide affinity chromatography for purification purposes. A highly purified antiserum was subsequently obtained through this process.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
Celluar localization	Extracellular region or secreted;
UniPort	P01282