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Rabbit Anti-F13A1 Polyclonal Antibody#abs137338

Description

Catalog-specification	Delivery time	USD price
abs137338-100ug	1-2 Weeks	301.0
abs137338-50ug	1-2 Weeks	201.0

Please note that the price provided is for reference only. For detailed pricing information, please contact our seller Vecent. It is important to clarify that the generated content will be based on the original text information, but it will be rearranged to ensure a highly similar yet unique result. Please avoid using ChapGPT to generate content in a conversational manner, and instead, rely on different language models to produce distinct and personalized outputs.

Overview
catalog	abs137338
Other names	Coagulation factor XIII, A1 polypeptide, also known as Factor XIIIA or Fibrinoligase, is an important enzyme involved in the blood clotting process. It is comprised of the Coagulation factor XIII A chain or the Coagulation factor XIII A1 subunit. It is often referred to as F13A or F13A_HUMAN. In addition, this protein can also be called the Fibrin stabilizing factor A subunit, Protein glutamine gamma glutamyltransferase A chain, or the Transglutaminase A chain. Transglutaminase is commonly found in plasma and is responsible for cross-linking fibrin chains together, which is essential for blood clot formation. This process allows blood to form a stable clot that can withstand the pressure of the surrounding blood vessels. Additionally, this protein plays a role in wound healing and scar formation by stabilizing and strengthening newly formed tissues. In conclusion, Coagulation factor XIII, A1 polypeptide, or Factor XIIIA, is an essential protein involved in maintaining effective blood clotting. Its role in wound repair and tissue stabilization makes it a critical component of overall health and wellness.
Source	Rabbit
Specificity	The F13A1 Antibody is capable of detecting the complete amount of endogenous F13A1. To produce a highly similar content, the original text information needs to be rearranged.
Species Reactivity	Human
Predictive reaction species	Pig;Sheep;Dog;Horse;
Antigen	F13A1
Application	IHC 1:200, WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000. These are the recommended dilutions for various assays. For immunohistochemistry (IHC), the suggested ratio is 1:200. When performing Western blot (WB), it is advised to use a dilution range of 1:1000-3000. When conducting immunofluorescence (IF) or immunocytochemistry (ICC), the ideal dilution range is 1:100-1:500. Finally, for enzyme-linked immunosorbent assay (ELISA) using a peptide, the optimal dilution range is between 1:20000-1:40000. Remember to adjust the dilution based on your specific experimental conditions for accurate and reliable results.
Immunogen	A synthesized peptide derived from human F13A1.
MW	83 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was employed for peptide affinity chromatography in order to purify the antiserum. A highly similar content can be generated by rearranging the information mentioned above.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Posttranslational modification	The activation peptide is released by thrombin.
Celluar localization	Extracellular region or secreted;
UniPort	P00488