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Rabbit Anti-ENOSF1 Polyclonal Antibody#abs139710

Description

Catalog-specification	Delivery time	USD price
abs139710-100ug	1-2 Weeks	301.0
abs139710-50ug	1-2 Weeks	201.0

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Overview
catalog	abs139710
Other names	I will generate a highly similar content by rearranging the information provided: Thymidylate synthase is targeted by antisense RNA. It is also known as ENOF1_HUMAN, Enolase superfamily member 1, ENOSF 1, enosf1, HSRTSBETA, Mitochondrial enolase superfamily member 1, RTS alpha, RTS, RTS beta, RTS beta protein, and TYMSAS. This enzyme plays a crucial role in DNA synthesis by catalyzing the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP). The inhibition of thymidylate synthase can be achieved through the use of antisense RNA, which targets the messenger RNA (mRNA) encoding this enzyme. This approach can potentially be used as a therapeutic strategy for certain diseases, including cancer. By targeting thymidylate synthase, antisense RNA can disrupt the production of dTMP, leading to impaired DNA synthesis and cell proliferation. Further research is needed to explore the potential of antisense RNA against thymidylate synthase as a therapeutic intervention.
Source	Rabbit
Specificity	The total ENOSF1 levels present in the body can be detected using the ENOSF1 antibody, which specifically targets the endogenous ENOSF1 protein. To rephrase this information, you could say: The ENOSF1 antibody is effective in detecting the natural levels of total ENOSF1 found within the body. It interacts specifically with endogenous ENOSF1, allowing researchers to effectively measure its presence.
Species Reactivity	Human
Predictive reaction species	Xenopus
Antigen	ENOSF1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human ENOSF1.
MW	50 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to keep this product in a freezer at a temperature of -20 °C for up to one year. To prevent any potential damage, refrain from subjecting the product to repeated cycles of freezing and thawing.
Storage buffer	To maintain the stability of Rabbit IgG, it is recommended to store it at -20 °C in a solution containing phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This storage condition allows for a shelf life of 12 months from the date of receipt. Ensuring proper storage is crucial for preserving the integrity and functionality of the antibody.
Target
Background	Plays a role in the catabolism of L-fucose, a sugar that is part of the carbohydrates that are attached to cellular glycoproteins. Catalyzes the dehydration of L-fuconate to 2-keto-3-deoxy-L-fuconate by the abstraction of the 2-proton to generate an enediolate intermediate that is stabilized by the magnesium ion (PubMed:24697329).
Posttranslational modification	Could be sumoylated.
Celluar localization	Mitochondrion;
UniPort	Q7L5Y1