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Rabbit Anti-PABPC4 Polyclonal Antibody#abs139282

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Description

Catalog-specification	Delivery time	USD price
abs139282-100ug	1-2 Weeks	301.0
abs139282-50ug	1-2 Weeks	201.0

Overview
catalog	abs139282
Other names	The protein commonly known as Activated platelet protein 1 is also referred to as APP-1, APP1, FLJ43938, Inducible poly(A) binding protein, iPABP, IPABP4, PABP 4, PABP-4, PABP4_HUMAN, PABPC 4, PABPC4, Poly A binding protein cytoplasmic 4, Poly(A) binding protein 4, Poly(A) binding protein cytoplasmic 4 (inducible form), Poly(A) binding protein cytoplasmic 4, Poly(A)-binding protein 4, Polyadenylate binding protein 4, Polyadenylate-binding protein 4, Polyadenylate-binding protein, cytoplasmic, 4, and Polyadenylate-binding protein, inducible. These various names all refer to the same protein which plays a role in binding to polyadenylate sequences in mRNA molecules and regulating their translation.
Source	Rabbit
Specificity	The total amount of PABPC4 in the body can be detected by using the PABPC4 Antibody, which is capable of recognizing endogenous levels of this protein. By rearranging the information presented above, we can convey the same message in a different manner, highlighting the importance of PABPC4 detection for various applications.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Chicken;Rabbit;Pig;Dog;Horse;Bovine;Sheep;
Antigen	PABPC4
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human PABPC4.
MW	71 kDa
Properties
Concentration	1mg/ml
purification	Through leveraging SulfoLink™ Coupling Resin, the antiserum was successfully purified via peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).
Tissue specificity	Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated.
Posttranslational modification	Arg-518 is dimethylated, probably to asymmetric dimethylarginine.
Celluar localization	Cytosol;Nucleus;
UniPort	Q13310