Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-DNA Pol Lambda Polyclonal Antibody#abs140409

Please note that the price mentioned above is for your reference only. For detailed pricing information, we suggest you contact our seller Vecent. It's important to understand that the price quoted may vary depending on several factors, and we want to ensure that you receive accurate...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs140409-100ug	1-2 Weeks	301.0
abs140409-50ug	1-2 Weeks	201.0

Overview
catalog	abs140409
Other names	DNA polymerase beta N is a variant of DNA polymerase beta, also known as DNA polymerase lambda or DNA polymerase beta-2. It is classified as EC 2.7.7.7 and EC 4.2.99., and is encoded by various gene names including BETAN, DPOLL_HUMAN, FLJ46002, OTTHUMP00000020321, OTTHUMP00000020323, OTTHUMP00000059179, Pol beta2, POL KAPPA, Pol Lambda, and POLKAPPA. DNA polymerase beta N has a similar function to other DNA polymerases, such as DNA polymerase kappa, in that it catalyzes the replication of DNA molecules. However, it also exhibits distinct properties, making it a unique member of the DNA polymerase family. Further research is needed to fully understand the specific role of DNA polymerase beta N in cellular processes.
Source	Rabbit
Specificity	The total DNA pol λ levels can be detected using the DNA pol λ Antibody, which specifically targets the endogenous levels of the enzyme.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Horse;Bovine;
Antigen	DNA pol lambda
Application	WB1:1000，IF/ICC1:100-1:500，ELISA（）1:20000-1:40000。，。，。
Immunogen	DNAλ（peptide），，。，ChapGPT，。
MW	63kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was purified through peptide affinity chromatography. A highly specific and efficient purification process, it ensures that only the desired peptide sequences are captured and isolated. This high-quality purification method ensures that the resulting antiserum is of exceptional purity and efficacy.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is advised to store it at a temperature of -20 °C for a period of one year. It is important to bear in mind avoiding repeated cycles of freezing and thawing as this could diminish the effectiveness of the product.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	DNA polymerase that functions in several pathways of DNA repair (PubMed:11457865, PubMed:19806195, PubMed:20693240). Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA (PubMed:11457865, PubMed:19806195). Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination (PubMed:19806195, PubMed:20693240). Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities (PubMed:10982892, PubMed:10887191, PubMed:12809503, PubMed:14627824, PubMed:15537631, PubMed:19806195). Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity (PubMed:11457865, PubMed:19806195).
Tissue specificity	Expressed in a number of tissues. Abundant in testis.
Celluar localization	Nucleus;
UniPort	Q9UGP5