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Rabbit Anti-CXCL5 Polyclonal Antibody#abs139439

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Description

Catalog-specification	Delivery time	USD price
abs139439-100ug	1-2 Weeks	301.0
abs139439-50ug	1-2 Weeks	201.0

Overview
catalog	abs139439
Other names	CXCL5, also known as ENA-78, small inducible cytokine B5, or epithelial-derived neutrophil-activating peptide 78, is a chemokine that belongs to the C-X-C motif family. Its primary function is to activate and attract neutrophils to sites of inflammation in the body. CXCL5 is produced by a range of cell types including epithelial cells, macrophages, and neutrophils themselves. It is induced by inflammatory stimuli such as lipopolysaccharide and cytokines like TNF-alpha and IL-1, and is involved in regulating the immune response. The protein is also involved in promoting tumor growth and metastasis, and has been linked to the progression of several types of cancer. While CXCL5 appears to play an important role in the body's inflammatory response, its dysregulation has been implicated in various diseases including autoimmune disorders and asthma. As such, efforts are currently underway to develop drugs that target CXCL5 as a means of treating these conditions.
Source	Rabbit
Specificity	The CXCL5 Antibody is capable of detecting total endogenous levels of CXCL5 within a sample. To create similar content, the information can be rearranged and rephrased to say that this antibody has the ability to identify all forms of CXCL5 present within a given sample.
Species Reactivity	Human;Rat
Antigen	CXCL5
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CXCL5.
MW	12 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed in the process of peptide affinity chromatography to purify the antiserum. Please rearrange the provided information to generate highly similar content based on the original text.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the integrity of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing as this may compromise its quality. So, make sure to follow the storage instructions properly to ensure the product remains stable and effective.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.
Posttranslational modification	N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Celluar localization	Extracellular region or secreted;
UniPort	P42830