Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-CPSF6 Polyclonal Antibody#abs138917

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller, Vecent. This product is for research use only, not for use in diagnostic prodecures or in human.

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs138917-100ug	1-2 Weeks	301.0
abs138917-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller, Vecent.

Overview
catalog	abs138917
Other names	The protein CFIM, also known as CFIm68, is a crucial component of the cleavage and polyadenylation specificity factor (CPSF) complex. With a molecular weight of 68 kDa, CFIM is one of the subunits of CPSF essential for efficient pre-mRNA processing. Besides its role in pre-mRNA cleavage, CFIM has also been identified as a key player in regulating gene expression and alternative splicing. In some studies, CFIM has been referred to as HPBRII-4/7 due to its association with the Hepatitis B virus regulatory protein. Overall, CFIM plays a crucial role in controlling gene expression by governing pre-mRNA processing and thereby impacting protein synthesis.
Source	Rabbit
Specificity	The total CPSF6 levels present in the body can be detected using the CPSF6 Antibody, which is capable of identifying the endogenous levels of the protein. It is important to note that this antibody can provide accurate results when analyzing the total CPSF6 levels in an organism. By using this antibody, researchers can gain insights into the functioning of this protein in the body, which could lead to new breakthroughs in medical research.
Species Reactivity	Human;Mouse
Predictive reaction species	Bovine;Dog;Horse
Antigen	CPSF6
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CPSF6.
MW	59 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography for purification. A highly purified antiserum was obtained through this process.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to store at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freezing and thawing cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping.
Celluar localization	Nucleus;
UniPort	Q16630