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Rabbit Anti-CDKL2 Polyclonal Antibody#abs133681

Description

Catalog-specification	Delivery time	USD price
abs133681-100ug	1-2 Weeks	301.0
abs133681-50ug	1-2 Weeks	201.0

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Overview
catalog	abs133681
Other names	CDKL2, also known as CDC2 related kinase or cyclin-dependent kinase-like 2, is a serine/threonine protein kinase that plays a crucial role in regulating cell cycle progression and cell proliferation. It is also involved in neuronal development and differentiation. The protein kinase p56 KKIAMRE, which is produced by CDKL2, has been shown to regulate the activity of other proteins involved in the cell cycle, such as cyclin-dependent kinases and tumor suppressors. Additionally, CDKL2 has been linked to the development of certain cancers and neurological disorders. Overall, CDKL2 is an important protein kinase with diverse cellular functions and significant implications for human health. Further research is needed to fully understand its role in disease and to develop targeted therapies that can exploit its activity for therapeutic benefit.
Source	Rabbit
Specificity	The total levels of endogenous CDKL2 can be successfully identified using the CDKL2 Antibody.
Species Reactivity	Human;Mouse;Rat
Antigen	CDKL2
Application	For Western Blot, dilution ratios of 1:500 to 1:1000 are recommended. For Immunofluorescence and Immunocytochemistry, optimal dilutions are within the range of 1:100 to 1:500. When using ELISA with peptide, it is recommended to dilute at a range of 1:20000 to 1:40000. These dilutions are suggested as a starting point and may require optimization for each individual experiment.
Immunogen	A synthesized peptide.
MW	56 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent peptide affinity chromatography purification. This process was used to isolate and purify the molecule of interest for further analysis and study. The resulting purified antiserum can now be used for various laboratory applications, such as in vitro diagnostic assays and immunotherapy treatments.
Clonality	Polyclonal Antibody
Stability & Storage	-20°C。/。，。
Storage buffer	This product contains Rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20°C and it remains stable for a period of 12 months from the date of receipt. The solution has been developed to have a high degree of similarity to the original text by rearranging the information provided.
Target
Background	ATP + a protein = ADP + a phosphoprotein.
Tissue specificity	Expressed in testis and kidney, and at lower level in brain and lung.
Celluar localization	Cytoskeleton;Nucleus;
UniPort	Q92772