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Rabbit Anti-Caspase-2 Polyclonal Antibody#abs133247

Description

Catalog-specification	Delivery time	USD price
abs133247-100ug	1-2 Weeks	301.0
abs133247-50ug	1-2 Weeks	201.0

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Overview
catalog	abs133247
Other names	CASP 2, also known as CASP-2, Casp2, CASP2_HUMAN, or Caspase 2, is an apoptosis-related cysteine peptidase. It is also referred to as Caspase-2 subunit p12, Caspase2, ICH 1, ICH 1 protease, ICH 1L, ICH1, ICH1 protease, ICH1L, NEDD-2, NEDD2, Neural precursor cell-expressed developmentally down-regulated protein 2, PPP1R57, Protease ICH-1, or Protein phosphatase 1 regulatory subunit 57.
Source	Rabbit
Specificity	The total levels of endogenous Caspase-2 can be detected using the Caspase-2 Antibody. This antibody is highly effective in identifying the presence of Caspase-2 in samples.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Sheep;Dog;Horse;
Antigen	Caspase-2
Application	The dilution for Western Blot is recommended to be 1:1000-3000, for Immunohistochemistry it is 1:200, for Immunocytochemistry/Immunofluorescence it is suitable, and for ELISA (peptide) it is suggested to be 1:20000-1:40000. It is important to follow these guidelines to ensure accurate and reliable results in the experiments.
Immunogen	A peptide that has been synthesized from human Caspase-2 can be found in the field of biotechnology and molecular biology. This peptide is derived from the structure of Caspase-2, an enzyme that plays an important role in programmed cell death or apoptosis. By synthesizing this peptide, researchers are able to explore the biochemical properties and functions of Caspase-2 in more detail. The synthesized peptide is highly similar to the natural form of Caspase-2 and is used in various research studies and experiments. Through its use, scientists hope to better understand the role of Caspase-2 in apoptosis and other biological processes.
MW	48,30,12kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the peptide affinity chromatography process to purify the antiserum. The purified antiserum is now available for further analysis and experimentation.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to keep the product at a temperature of -20 °C for up to a year. To maintain the product's efficacy, it is advised to avoid multiple rounds of freeze/thaw cycles. Be sure to follow these guidelines for optimal product storage.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Tissue specificity	High level expression seen in the embryonic CNS, liver, lung, kidney, small intestine, and hair follicles of vibrissae. Moderate expression seen in the skin, oral mucosa, skeletal muscle, submandibular gland and thymus. In the adult, it is highly expressed in spleen, lung and kidney. Moderately in the brain, heart, testis, liver. Low levels in the thymus, skeletal muscle, ovary and gut.
UniPort	P29594