Rabbit Anti-Casein Kinase Igamma1 Polyclonal Antibody#abs140387

Rabbit Anti-Casein Kinase Igamma1 Polyclonal Antibody#abs140387

Please note that the price mentioned above is for your reference only. In order to obtain detailed pricing information, we kindly ask you to get in touch with our seller, Vecent. Feel free to reach out to him for all the specific pricing details you require. Western blot analysis Casein Kinase...

Description

Catalog-specificationDelivery timeUSD price

abs140387-100ug

1-2 Weeks

301.0

abs140387-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is for your reference only. In order to obtain detailed pricing information, we kindly ask you to get in touch with our seller, Vecent. Feel free to reach out to him for all the specific pricing details you require.


Overview

catalog

abs140387
Other namesCSNK1G1, also known as casein kinase 1 gamma 1 or CKI gamma 1, is an isoform of casein kinase I that plays a crucial role in regulating various cellular processes such as cell division and circadian rhythms. This protein, encoded by the 9130020E21Rik gene, functions as a serine/threonine kinase and is responsible for phosphorylating a variety of substrates. CKI gamma 1 is highly conserved across species, indicating its importance in maintaining cellular homeostasis. Mutations in this gene have been associated with various diseases, including cancer and neurological disorders. Understanding the function of CKI gamma 1 is crucial in developing new therapeutic approaches to treat these conditions.
SourceRabbit
SpecificityThe detection of endogenous levels of total Casein Kinase Igamma1 can be achieved using the Casein Kinase Igamma1 Antibody. This antibody specifically targets and recognizes the total amount of Casein Kinase Igamma1 present in a sample. By utilizing this antibody, researchers can accurately assess and quantify the levels of Casein Kinase Igamma1 within their experimental systems. The ability to detect endogenous levels of this protein is crucial for understanding its role and function in various cellular processes and signaling pathways. Therefore, the Casein Kinase Igamma1 Antibody provides a valuable tool for investigating the functions and regulation of Casein Kinase Igamma1 in biological systems.
Species ReactivityHuman;Mouse;Rat;Monkey
Predictive reaction speciesRabbit;Dog;Horse
AntigenCasein Kinase Igamma1
ApplicationThe recommended dilution for WB is 1:1000, while for IF/ICC it ranges from 1:100 to 1:500. The peptide ELISA assay requires a dilution of 1:20000 to 1:40000. To ensure accuracy, it is important to follow these dilution guidelines when conducting experiments using these techniques.
ImmunogenCasein Kinase Igamma1-derived synthesized peptide from human shows remarkable similarity. Upholding the original text information, let me present an alternative speech style through a substantially unique content generation technique.
MW49kDa
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was utilized in purifying the antiserum through peptide affinity chromatography.
ClonalityPolyclonal Antibody
Stability & StorageTo maintain the quality of the product, it is recommended to keep it at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting it to multiple freeze/thaw cycles.
Storage bufferStore this rabbit IgG in a solution of phosphate-buffered saline at a pH of 7.4, which includes 150mM NaCl, 0.02% sodium azide, and 50% glycerol. Keep the solution at a temperature of -20 °C, and it will remain stable for up to 12 months from the original date of receipt.

Target

Background

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN.

Posttranslational modificationAutophosphorylated.
Celluar localizationCytosol;Nucleus;
UniPortQ9HCP0


Western blot analysis Casein Kinase Igamma1 using COS7 whole cell lysates


This product is for research use only, not for use in diagnostic prodecures or in human.


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